Evidence map›Paper›PMID 35142341›Full record

ArticleAmerican journal of epidemiology2022

Racial/Ethnic and Geographic Trends in Combined Stimulant/Opioid Overdoses, 2007-2019.

Tarlise Townsend, David Kline, Ariadne Rivera-Aguirre, Amanda M Bunting, Pia M Mauro, Brandon D L Marshall, Silvia S Martins, Magdalena Cerdá

Open access · greenAbstract read
In one paragraph

Article in American journal of epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 1 pooled it
16.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 1 synthesis or guideline pooled it, 113 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Effects of opioids and stimulants on the respiratory system.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  4. Article
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  8. Review
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18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Tarlise Townsend
David Kline
Ariadne Rivera-Aguirre
Amanda M Bunting
Pia M Mauro
Brandon D L Marshall
Silvia S Martins
Magdalena Cerdá

Funding

BEHAVIORAL SCI TRAINING IN DRUG ABUSE RESEARCHT32DA007233 · NIDA · PUBLIC HEALTH SOLUTIONS · PI GOLDSAMT, LLOYD A · 1985 to 2023
$20.2M
Reducing Drug-Related Mortality Using Predictive Analytics: A Randomized, Statewide, Community Intervention TrialR01DA046620 · NIDA · BROWN UNIVERSITY · PI CERDA, MAGDALENA, MARSHALL, BRANDON DAVID LEWIS · 2019 to 2023
$3.8M
The Lifespan/Brown Criminal Justice Research Program on Substance Use and HIVR25DA037190 · NIDA · MIRIAM HOSPITAL · PI CURT G BECKWITH · 2014 to 2026
$3.5M
Development of a novel polysubstance assessment tool for vulnerable subpopulationsK01DA053435 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BUNTING, AMANDA M · 2021 to 2025
$909k
Multi-level associations between medical marijuana laws and substance use disorder treatmentK01DA045224 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAURO, PIA M. · 2018 to 2022
$878k
A Bayesian Spatio-Temporal Approach for Estimating County-Level Opioid Misuse Rates in OhioR21DA045236 · NIDA · OHIO STATE UNIVERSITY · PI HEPLER, STACI, KLINE, DAVID M · 2018 to 2019
$461k
NIDA NIH HHS K01 DA045224NIDA NIH HHS K01 DA053435NIDA NIH HHS R01 DA046620NIDA NIH HHS R21 DA045236NIDA NIH HHS R25 DA037190NIDA NIH HHS T32 DA007233
6 · The paper itself

Abstract

In the United States, combined stimulant/opioid overdose mortality has risen dramatically over the last decade. These increases may particularly affect non-Hispanic Black and Hispanic populations. We used death certificate data from the US National Center for Health Statistics (2007-2019) to compare state-level trends in overdose mortality due to opioids in combination with 1) cocaine and 2) methamphetamine and other stimulants (MOS) across racial/ethnic groups (non-Hispanic White, non-Hispanic Black, Hispanic, and non-Hispanic Asian American/Pacific Islander). To avoid unstable estimates from small samples, we employed principles of small area estimation and a Bayesian hierarchical model, enabling information-sharing across groups. Black Americans experienced severe and worsening mortality due to opioids in combination with both cocaine and MOS, particularly in eastern states. Cocaine/opioid mortality increased 575% among Black people versus 184% in White people (Black, 0.60 to 4.05 per 100,000; White, 0.49 to 1.39 per 100,000). MOS/opioid mortality rose 16,200% in Black people versus 3,200% in White people (Black, 0.01 to 1.63 per 100,000; White, 0.09 to 2.97 per 100,000). Cocaine/opioid overdose mortality rose sharply among Hispanic and Asian Americans. State-group heterogeneity highlighted the importance of data disaggregation and methods to address small sample sizes. Research to understand the drivers of these trends and expanded efforts to address them are needed, particularly in minoritized groups.

Indexed as

Drug OverdoseOpiate OverdoseBayes TheoremEthnicityHumansRacial GroupsUnited Statesdrug overdoseharm reductionopioidspsychostimulantsracial disparitiessubstance use

Identifiers

PMID35142341
PMCPMC9077116
OpenAlexW4205092055

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.