SynthesisAlzheimer's & dementia : the journal of the Alzheimer's Association2022
Mechanisms of motoric cognitive risk-Hypotheses based on a systematic review and meta-analysis of longitudinal cohort studies of older adults.
Synthesis in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Mechanisms of motoric cognitive risk-Hypotheses based on a systematic review and meta-analysis of longitudinal cohort studies of older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022Pooled it
- Non-literacy biased, culturally fair cognitive detection tool in primary care patients with cognitive concerns: a randomized controlled trial.Nature medicine · 2024Trial
- Prevalence and Influencing Factors of Motoric Cognitive Risk Syndrome Among Older Adults in Long-Term Care Facilities.Healthcare (Basel, Switzerland) · 2026Article
- Age-friendly environments and incident motoric cognitive risk syndrome in older adults: A prospective cohort study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Reported Slowing in Walking and Everyday Activities and Long-Term Mortality in Older Adults: The NEDICES Population-Based Cohort Study.Medical sciences (Basel, Switzerland) · 2026Article
- The association between sarcopenia, sedentary behavior, and the motor cognitive risk syndrome: A Mendelian randomization study.Medicine · 2026Article
- Proactive health management strategies for older adults with motoric cognitive risk syndrome: a scoping review.BMC geriatrics · 2025Article
- Cognitive and physical functions among Chinese community-dwelling older adults with motoric cognitive risk syndrome: A prospective cohort study.International journal of nursing sciences · 2025Article
- From Dual Decline to Clinical Consequences: Mechanistic Pathways and Health Outcomes of Motoric Cognitive Risk Syndrome.Aging and disease · 2025Review
- Pulmonary function and motoric cognitive risk syndrome in older adults.Scientific reports · 2025Article
- Cortical Hemodynamic Abnormalities Associated With Fine Motor Deficits in Mild Cognitive Impairment.CNS neuroscience & therapeutics · 2025Article
- Motoric cognitive risk syndrome: A review of fall risk assessment and management strategies.World journal of psychiatry · 2025Review
- Clinical, biological, and neuroimaging profiles for motoric cognitive risk syndrome in older adults: The MIND-China study.Journal of internal medicine · 2025Article
- Electrocardiographic markers in Motoric Cognitive Risk syndrome.Gerontology · 2025Article
- Association between personality profiles and motoric cognitive risk syndrome in community-dwelling older adults: a person-centered approach.BMC psychiatry · 2025Article
- Subjective motoric cognitive risk syndrome: Preliminary prevalence from an online survey of a German cohort aged 50.Journal of Alzheimer's disease : JAD · 2025Article
- The Timed Up and Go dual-task test's cognitive and motor outcomes show promising test-retest reliability in older adults with perceived memory impairment.Frontiers in aging · 2025Article
- Combined association of gait speed and processing speed on cardiometabolic disease mortality risk in the US older adults: a prospective cohort study from NHANES.Frontiers in aging neuroscience · 2025Article
- Chronic Cerebral Deterioration - A Comprehensive View of Old-Age Cerebral Deterioration.Aging and disease · 2024Review
- Association between Motoric Cognitive Risk Syndrome and Indicators of Reflecting Independent Living among Community-Dwelling Older Adults in Japan: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We aimed to refine the hypothesis that motoric cognitive risk (MCR), a syndrome combining measured slow gait speed and self-reported cognitive complaints, is prognostic of incident dementia and other major causes of morbidity in older age. We propose mechanisms on the relationship between motor and cognitive function and describe a roadmap to validate these hypotheses. We systematically searched major electronic databases from inception to August 2021 for original longitudinal cohort studies of adults aged ≥60 years that compared an MCR group to a non-MCR group with any health outcome. Fifteen cohorts were combined by meta-analysis. Participants with MCR were at an increased risk of cognitive impairment (adjusted hazard ratio [aHR] 1.76, 95% CI 1.49-2.08; I
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.