ReviewNorth American Spine Society journal2021
The influence of comorbidities on the treatment outcome in symptomatic lumbar spinal stenosis: A systematic review and meta-analysis.
Review in North American Spine Society journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- Phenotypes of patients with symptomatic lumbar spinal stenosis presenting for nonoperative care: baseline data from the Lumbar Stenosis Prognostic Subgroups for Personalizing Care and Treatment Study (PROSPECTS).Pain medicine (Malden, Mass.) · 2026Article
- Patient-reported outcomes and their associated factors at 1- and 2-year follow-up after lumbar spine surgery: a surgery registry study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Neighborhood socioeconomic disadvantage is not associated with adverse outcomes following elective spine surgery in older Veterans.North American Spine Society journal · 2025Article
- Investigating the Effect of Lumbar Spinal Stenosis (LSS) Surgery on Sexual Function in Male Patients over 50 Years.Medicina (Kaunas, Lithuania) · 2025Article
- The impact of preoperative handgrip strength on postoperative outcomes following transforaminal lumbar interbody fusion.Journal of orthopaedic surgery and research · 2025Observational
- Lumbar Spinal Stenosis: Pathophysiology, Biomechanics, and Innovations in Diagnosis and Management.Journal of spine research and surgery · 2025Article
- Care Fragmentation, Social Determinants of Health, and Postoperative Mortality in Older Veterans.The Journal of surgical research · 2024Article
- Percutaneous image-guided lumbar decompression and outpatient laminectomy for the treatment of lumbar spinal stenosis: a 2-year Medicare claims benchmark study.Interventional pain medicine · 2024Article
- Lumbar Decompression versus Decompression and Fusion in Octogenarians: Complications and Clinical Course With 3-Year Follow-Up.Global spine journal · 2024Article
- Mechanical Needling With Sterile Water Versus Lidocaine Injection for Lumbar Spinal Stenosis.Global spine journal · 2024Article
- Correction of Spinal Sagittal Alignment after Posterior Lumbar Decompression: Does Severity of Central Canal Stenosis Matter?Asian spine journal · 2023Article
- Comparing 30-Day Outcomes After Emergent Spine Procedures Performed "During Hours" vs "After Hours".International journal of spine surgery · 2023Article
- Comorbidity data collection across different spine registries: an evidence map.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Review
- Surgery rates for lumbar spinal stenosis in Denmark between 2002 and 2018: a registry-based study of 43,454 patients.Acta orthopaedica · 2022Article
- The influence of comorbidities on the treatment outcome in symptomatic lumbar spinal stenosis: A systematic review and meta-analysis.North American Spine Society journal · 2021Review
- Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLumbar spinal stenosis (LSS) affects mainly elderly patients. To this day, it is unclear whether comorbidities influence treatment success. The aim of this systematic review and meta-analysis was to assess the impact of comorbidities on the treatment effectiveness in symptomatic LSS.
methodsWe conducted a systematic review and meta-analysis and reviewed prospective or retrospective studies from Medline, Embase, Cochrane Library and CINAHL from inception to May 2020, including adult patients with LSS undergoing surgical or conservative treatment. Main outcomes were satisfaction, functional and symptoms improvement, and adverse events (AE). Proportions of outcomes within two subgroups of a comorbidity were compared with risk ratio (RR) as summary measure. Availability of ≥3 studies for the same subgroup and outcome was required for meta-analysis.
resultsOf 72 publications, 51 studies, mostly assessing surgery, there was no evidence reported that patients with comorbidities were less satisfied compared to patients without comorbidities (RR 1.06, 95% confidence interval (CI) 0.77 to 1.45,
conclusionIn patients with LSS and comorbidities (in particular diabetes), a higher risk for AE should be considered in the treatment decision. Older age alone was not associated with an increased risk for AE, less functional and symptoms improvement, and less treatment satisfaction.
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Registered trials
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