Evidence map›Paper›PMID 35141475›Full record

ArticleFASEB bioAdvances2022

Maternal

Mahesh Krishna, Melinda Engevik, Karen Queliza, Savini Britto, Rajesh Shah, Wenly Ruan, Hongtao Wang, James Versalovic, Richard Kellermayer

Open access · goldAbstract read
In one paragraph

Article in FASEB bioAdvances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Early life factors, diet and microbiome, and risk of inflammatory bowel disease.Journal of the Canadian Association of Gastroenterology · 2025
    Article
  5. The treatment naïve microbiome of pediatric ulcerative colitis and microbial therapeutics: A humbling challenge.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025
    Article
  6. Evaluating the Therapeutic Efficacy ofCurrent pharmaceutical design · 2025
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. MaternalFASEB bioAdvances · 2022
    Article
  12. Gut microbes
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Mahesh KrishnaJohns Hopkins School of Medicine Baltimore Maryland USA.ORCID https://orcid.org/0000-0001-9762-5717
Melinda EngevikDepartment of Pathology & Immunology Baylor College of Medicine Houston Texas USA.
Karen QuelizaPediatric Gastroenterology, Hepatology and Nutrition Memorial Sloan Kettering Cancer Center New York New York USA.
Savini BrittoSection of Pediatric Gastroenterology Baylor College of Medicine Houston Texas USA.
Rajesh ShahDepartment of Medicine Baylor Scott and White Austin Texas USA.
Wenly RuanSection of Pediatric Gastroenterology Baylor College of Medicine Houston Texas USA.
Hongtao WangSection of Pediatric Gastroenterology Baylor College of Medicine Houston Texas USA.
James VersalovicDepartment of Pathology & Immunology Baylor College of Medicine Houston Texas USA.
Richard KellermayerSection of Pediatric Gastroenterology Baylor College of Medicine Houston Texas USA.
Baylor College of Medicine · USBaylor Medical Center at Garland · USJohns Hopkins University · USMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
The role of SMAD1 and SATB2 in colon patterningP20GM130457 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI STEPHEN A DUNCAN · 2020 to 2026
$18.7M
Proteomics CoreP30DK123704 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI DON C. ROCKEY · 2020 to 2026
$8.8M
NCI NIH HHS P30 CA008748NIDDK NIH HHS P30 DK123704NIGMS NIH HHS P20 GM130457
6 · The paper itself

Abstract

The purpose of our experiment was to explore how stochastic (inter-individual variation) gut microbiome composition may link to inflammatory bowel disease (IBD) susceptibility and guide the development of a perinatal preventative probiotic. Dextran sodium sulfate (DSS) was introduced to C57BL/BJ mice to induce acute colitis as a model of IBD. Potentially protective bacteria were identified using a discovery-validation cohort approach toward stochastic DSS susceptibility.

Indexed as

inflammatory bowel diseaseLactobacillusmicrobiotapediatricprobioticstochastic

Identifiers

PMID35141475
PMCPMC8814561
OpenAlexW3207891717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.