Evidence map›Paper›PMID 35141446›Full record

ArticleDevelopment & reproduction2021

Specific Biological Activity of Equine Chorionic Gonadotropin (eCG) Glycosylation Sites in Cells Expressing Equine Luteinizing Hormone/CG (eLH/CG) Receptor.

Munkhzaya Byambaragchaa, Seung-Hee Choi, Hyo-Eun Joo, Sang-Gwon Kim, Yean-Ji Kim, Gyeong-Eun Park, Myung-Hwa Kang, Kwan-Sik Min

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Development & reproduction, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Munkhzaya ByambaragchaaInstitute of Genetic Engineering, Hankyong National University, Ansung 17579, Korea.ORCID https://orcid.org/0000-0002-0277-1816
Seung-Hee ChoiAnimal Biotechnology, Hankyong National University, Ansung 17579, Korea.ORCID https://orcid.org/0000-0002-9550-6113
Hyo-Eun JooDept. of Animal Life Science, Hankyong National University, Ansung 17579, Korea.ORCID https://orcid.org/0000-0002-8387-0428
Sang-Gwon KimDept. of Animal Life Science, Hankyong National University, Ansung 17579, Korea.ORCID https://orcid.org/0000-0003-3976-0931
Yean-Ji KimDept. of Animal Life Science, Hankyong National University, Ansung 17579, Korea.ORCID https://orcid.org/0000-0002-8411-2100
Gyeong-Eun ParkDept. of Animal Life Science, Hankyong National University, Ansung 17579, Korea.ORCID https://orcid.org/0000-0003-1740-3036
Myung-Hwa KangDept. of Food Science and Nutrition, Hoseo University, Asan 31499, Korea.ORCID https://orcid.org/0000-0003-4309-3684
Kwan-Sik MinInstitute of Genetic Engineering, Hankyong National University, Ansung 17579, Korea.ORCID https://orcid.org/0000-0002-5451-3085
Hankyong National University · KRHoseo University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Equine chorionic gonadotropin (eCG), produced by the endometrial cups of the placenta after the first trimester, is a specific glycoprotein that displays dual luteinizing hormone (LH)-like and follicle-stimulating hormone (FSH)-like effects in non-equid species. However, in equidaes, eCG exhibits only LH-like activity. To identify the specific biological functions of glycosylated sites in eCG, we constructed the following site mutants of N- and O-linked glycosylation: eCGβ/αΔ56, substitution of α-subunit

Indexed as

Biological activityChinese hamster ovary suspension (CHO-S) cellsEquine luteinizing hormone/chorionic gonadotropin receptors (eLH/CGR)Glycosylation sitesrec-eCG

Identifiers

PMID35141446
PMCPMC8807129
OpenAlexW4210610241

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.