Evidence map›Paper›PMID 35141287›Full record

ArticleFrontiers in cardiovascular medicine2021

Exercise-Induced Cardiac Fatigue in Recreational Ultramarathon Runners at Moderate Altitude: Insights From Myocardial Deformation Analysis.

Sebastián Wolff, José M Picco, Leonel Díaz-González, Pedro L Valenzuela, Emanuel Gonzalez-Dávila, Alejandro Santos-Lozano, Pablo Matile, David Wolff, Araceli Boraita, Alejandro Lucia

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. TheFrontiers in physiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Sebastián WolffWolff Cardiology and Sport Medicine Institute, Mendoza, Argentina.
José M PiccoWolff Cardiology and Sport Medicine Institute, Mendoza, Argentina.
Leonel Díaz-GonzálezCardiology Department, CEMTRO Clinic, Madrid, Spain.
Pedro L ValenzuelaFaculty of Sport Sciences, Universidad Europea de Madrid, Madrid, Spain.
Emanuel Gonzalez-DávilaWolff Cardiology and Sport Medicine Institute, Mendoza, Argentina.
Alejandro Santos-LozanoI+HeALTH, European University Miguel de Cervantes, Valladolid, Spain.
Pablo MatileMatile Laboratory, Mendoza, Argentina.
David WolffWolff Cardiology and Sport Medicine Institute, Mendoza, Argentina.
Araceli BoraitaDepartment of Cardiology, Sports Medicine Center, Spanish Sports Health Protection Agency, Consejo Superior de Deportes, Madrid, Spain.
Alejandro LuciaFaculty of Sport Sciences, Universidad Europea de Madrid, Madrid, Spain.
Research Institute Hospital 12 de Octubre · ESHospital Universitario La Paz · ESUniversidad Europea Miguel de Cervantes · ESUniversity of Mendoza · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundControversy exists on the actual occurrence of exercise-induced cardiac fatigue (EICF) with ultraendurance exercise, as well as on whether factors such as age or training status might predispose to this condition. The present study aimed to assess the occurrence of EICF among recreational ultramarathon runners, as well as to determine potential predictive factors.

methodsNineteen male recreational runners (42 ± 12yrs) participated in a 55-km trial race at moderate altitude (1,800-2,500 m). Participants were evaluated before and after the race using Doppler echocardiography and myocardial deformation analysis. EICF was determined as a reduction >5% of either left ventricular global longitudinal strain (LVGLS) or right ventricular free wall strain (RVFWS). Demographical (age, body mass index), training (training experience, volume and intensity), competition (finishing time, relative intensity) and biochemical variables (blood lactate, creatine kinase [CK] and CK-MB) were assessed as predictors of EICF.

resultsA significant reduction in LVGLS (20.1 ± 2.1% at baseline vs. 18.8 ± 2.4% at post-race,

conclusionsUltramarathon running at moderate altitude seems to induce EICF in a considerable proportion of recreational athletes.

Indexed as

athlete's heartheart fatiguemyocardial deformationmyocardial strainultra-marathonventricular function

Identifiers

PMID35141287
PMCPMC8818846
OpenAlexW4207033701

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.