Evidence map›Paper›PMID 35141258›Full record

ReviewFrontiers in medicine2021

Pathogenesis of Anti-melanoma Differentiation-Associated Gene 5 Antibody-Positive Dermatomyositis: A Concise Review With an Emphasis on Type I Interferon System.

Huifang Hu, Hang Yang, Yi Liu, Bing Yan

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 4 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 4 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
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  5. Article
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  8. Review
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  12. COVID-19-Associated MDA5-Mediated Necrotizing Myositis.The American journal of case reports · 2025
    Article
  13. Effectiveness and safety of tofacitinibThe European respiratory journal · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Huifang HuDepartment of Rheumatology and Immunology, Rare Diseases Center, Frontiers Science Center for Disease-Related Molecular Network, Institute of Immunology and Inflammation, West China Hospital, Sichuan University, Chengdu, China.
Hang YangDepartment of Rheumatology and Immunology, Rare Diseases Center, Frontiers Science Center for Disease-Related Molecular Network, Institute of Immunology and Inflammation, West China Hospital, Sichuan University, Chengdu, China.
Yi LiuDepartment of Rheumatology and Immunology, Rare Diseases Center, Frontiers Science Center for Disease-Related Molecular Network, Institute of Immunology and Inflammation, West China Hospital, Sichuan University, Chengdu, China.
Bing YanDepartment of Rheumatology and Immunology, Rare Diseases Center, Frontiers Science Center for Disease-Related Molecular Network, Institute of Immunology and Inflammation, West China Hospital, Sichuan University, Chengdu, China.
Sichuan University · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis (MDA5

Indexed as

anti-MDA5 antibodyCADMIFN I systemMDA5+ DMpathogenesistype I IFN

Identifiers

PMID35141258
PMCPMC8818857
OpenAlexW4206983935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.