Evidence map›Paper›PMID 35141180›Full record

ArticleFrontiers in pediatrics2021

Case Report: Prevention of Rhabdomyolysis-Associated Acute Kidney Injury by Extracorporeal Blood Purification With Cytosorb

Simon Rauch, Andrea Borgato, Ewald Gruber, Carlo Leggieri, Matthias Bock, Paolo Mario Enrico Seraglio

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Novel extracorporeal therapies in children.Pediatric nephrology (Berlin, Germany) · 2026
    Article
  2. Article
  3. Article
  4. Rhabdomyolysis in Children: A State-of-the-Art Review.Children (Basel, Switzerland) · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Simon RauchDepartment of Anesthesia and Intensive Care Medicine, "F. Tappeiner" Hospital, Merano, Italy.
Andrea BorgatoDepartment of Anesthesia and Intensive Care Medicine, "F. Tappeiner" Hospital, Merano, Italy.
Ewald GruberDepartment of Surgery, "F. Tappeiner" Hospital, Merano, Italy.
Carlo LeggieriDepartment of Anesthesia and Intensive Care Medicine, "F. Tappeiner" Hospital, Merano, Italy.
Matthias BockDepartment of Anesthesia and Intensive Care Medicine, "F. Tappeiner" Hospital, Merano, Italy.
Paolo Mario Enrico SeraglioDepartment of Anesthesia and Intensive Care Medicine, "F. Tappeiner" Hospital, Merano, Italy.
Institute of Mountain Emergency Medicine · ITKrankenhaus Meran · ITParacelsus Medical University · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute kidney injury (AKI) is a severe complication of rhabdomyolysis. The pathophysiology of rhabdomyolysis-associated AKI is complex, but myoglobin related damage plays a major role. Extracorporeal removal of myoglobin is therefore an appealing target to prevent AKI, however, attempts to remove myoglobin with standard dialysis membranes have so far been disappointing. Here we report the case of a 12-year-old boy with severe trauma-related rhabdomyolysis where we successfully utilized continuous renal replacement therapy in combination with Cytosorb

Indexed as

acute kidney injuryblood purificationcrush injuryCytosorb®rhabdomyolysis

Identifiers

PMID35141180
PMCPMC8819180
OpenAlexW4207030488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.