Evidence map›Paper›PMID 35141179›Full record

ArticleFrontiers in pediatrics2021

Association Between Serum Lactate and Unsatisfactory Outcomes in Critically Ill Children in the Immediate Post-operative Period of Liver Transplantation.

Jaime Fernández-Sarmiento, María Angélica Wilches-Cuadros, Ricardo Hernandez-Sarmiento, Hernando Mulett, Karen Moreno-Medina, Nicolás Molano, Julián Augusto Palomar Dominguez, Lorena Acevedo, Claudia Salinas, Jairo Rivera

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jaime Fernández-SarmientoDepartment of Pediatrics and Intensive Care, Fundación Cardioinfantil-Instituto de Cardiología, Universidad de La Sabana, Bogotá, Colombia.
María Angélica Wilches-CuadrosDepartment of Pediatrics and Intensive Care, Fundación Cardioinfantil-Instituto de Cardiología, Universidad el Rosario, Bogotá, Colombia.
Ricardo Hernandez-SarmientoDepartment of Pediatrics and Intensive Care, Fundación Cardioinfantil-Instituto de Cardiología, Universidad de La Sabana, Bogotá, Colombia.
Hernando MulettDepartment of Pediatrics and Intensive Care, Fundación Cardioinfantil-Instituto de Cardiología, Universidad de La Sabana, Bogotá, Colombia.
Karen Moreno-MedinaResearch Department, Fundación CardioInfantil-Instituto de Cardiología, Bogotá, Colombia.
Nicolás MolanoClinical Research Group, School of Medicine and Health Sciences, Universidad del Rosario, Bogotá, Colombia.
Julián Augusto Palomar DominguezDepartment of Pediatrics, Universidad de La Sabana, Bogotá, Colombia.
Lorena AcevedoDepartment of Pediatrics and Intensive Care, Fundación Cardioinfantil-Instituto de Cardiología, Universidad de La Sabana, Bogotá, Colombia.
Claudia SalinasDepartment of Liver Transplantation, Fundación Cardioinfantil-Instituto de Cardiología, Bogotá, Colombia.
Jairo RiveraDepartment of Liver Transplantation, Fundación Cardioinfantil-Instituto de Cardiología, Bogotá, Colombia.
Institute of Cardiology · COUniversidad de La Sabana · COUniversidad del Rosario · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesSerum lactate is a useful biomarker of tissue perfusion in critically ill patients. We evaluated the behavior of serum lactate in children in the pediatric intensive care unit (PICU) immediately after liver transplantation and its association with surgical complications, graft dysfunction and 90-day mortality. MATERIALS AND

methodsA prospective observational study carried out between November 2009 and December 2019. Multidisciplinary PICU at the University Children's Hospital, Fundación Cardioinfantil-IC, Bogotá, Colombia. MEASUREMENTS AND MAIN

resultsPatients between 1 month and 18 years of age who were in the immediate post-operative period following living-donor or cadaveric liver transplantation were included. A total of 145 patients with a median age of 14 months (IQR 8-60) met the inclusion criteria. Biliary atresia was the main diagnosis in 56.5% of the cases. A serum lactate level > 3.0 mmol/L on admission to the PICU was associated with biliary complications (AUC 0.73 95% CI 0.54-0.93;

conclusionsIn post-operative pediatric liver transplant patients, the level of serum lactate is associated with post-operative surgical complications and mortality.

Indexed as

biliary atresiachildhypoxialiver failuremortalitytissue donor

Identifiers

PMID35141179
PMCPMC8818884
OpenAlexW4210728047

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.