Evidence map›Paper›PMID 35141147›Full record

ArticleFrontiers in oncology2021

Multi-Institutional Validation of Two-Streamed Deep Learning Method for Automated Delineation of Esophageal Gross Tumor Volume Using Planning CT and FDG-PET/CT.

Xianghua Ye, Dazhou Guo, Chen-Kan Tseng, Jia Ge, Tsung-Min Hung, Ping-Ching Pai, Yanping Ren, Lu Zheng, Xinli Zhu, Ling Peng and 15 more

Abstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Evaluation of PET-detected nodal upstaging and planning target volume expansion in esophageal cancer radiotherapy planning.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Xianghua YeDepartment of Radiation Oncology, The First Affiliated Hospital Zhejiang University, Hangzhou, China.
Dazhou GuoPAII Inc., Bethesda, MD, United States.
Chen-Kan TsengDepartment of Radiation Oncology, Chang Gung Memorial Hospital, Linkou, Taiwan.
Jia GeDepartment of Radiation Oncology, The First Affiliated Hospital Zhejiang University, Hangzhou, China.
Tsung-Min HungDepartment of Radiation Oncology, Chang Gung Memorial Hospital, Linkou, Taiwan.
Ping-Ching PaiDepartment of Radiation Oncology, Chang Gung Memorial Hospital, Linkou, Taiwan.
Yanping RenDepartment of Radiation Oncology, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Lu ZhengDepartment of Radiation Oncology, Lihuili Hospital, Ningbo Medical Center, Ningbo, China.
Xinli ZhuDepartment of Radiation Oncology, The First Affiliated Hospital Zhejiang University, Hangzhou, China.
Ling PengDepartment of Respiratory Disease, Zhejiang Provincial People's Hospital, Hangzhou, China.
Ying ChenDepartment of Radiation Oncology, The First Affiliated Hospital Zhejiang University, Hangzhou, China.
Xiaohua ChenDepartment of Radiation Oncology, The First Hospital of Lanzhou University, Lanzhou, China.
Chen-Yu ChouDepartment of Radiation Oncology, Chang Gung Memorial Hospital, Linkou, Taiwan.
Danni ChenDepartment of Radiation Oncology, The First Affiliated Hospital Zhejiang University, Hangzhou, China.
Jiaze YuDepartment of Radiation Oncology, Haining People's Hospital, Jiaxing, China.
Yuzhen ChenDepartment of Nuclear Medicine, Chang Gung Memorial Hospital, Linkou, Taiwan.
Feiran JiaoIndependent Researcher, Silver Spring, MD, United States.
Yi XinPing An Technology, Shenzhen, China.
Lingyun HuangPing An Technology, Shenzhen, China.
Guotong XiePing An Technology, Shenzhen, China.
Jing XiaoPing An Technology, Shenzhen, China.
Le LuPAII Inc., Bethesda, MD, United States.
Senxiang YanDepartment of Radiation Oncology, The First Affiliated Hospital Zhejiang University, Hangzhou, China.
Dakai JinPAII Inc., Bethesda, MD, United States.
Tsung-Ying HoDepartment of Nuclear Medicine, Chang Gung Memorial Hospital, Linkou, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe current clinical workflow for esophageal gross tumor volume (GTV) contouring relies on manual delineation with high labor costs and inter-user variability. PURPOSE: To validate the clinical applicability of a deep learning multimodality esophageal GTV contouring model, developed at one institution whereas tested at multiple institutions. MATERIALS AND

methodsWe collected 606 patients with esophageal cancer retrospectively from four institutions. Among them, 252 patients from institution 1 contained both a treatment planning CT (pCT) and a pair of diagnostic FDG-PET/CT; 354 patients from three other institutions had only pCT scans under different staging protocols or lacking PET scanners. A two-streamed deep learning model for GTV segmentation was developed using pCT and PET/CT scans of a subset (148 patients) from institution 1. This built model had the flexibility of segmenting GTVs

Indexed as

deep learningdelineationesophageal cancerPET/CT (18)F-FDGradiotherapysegmentation

Identifiers

PMID35141147
PMCPMC8820194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.