Evidence map›Paper›PMID 35141116›Full record

ArticlePreventive medicine reports2022

Simple cardiovascular risk stratification by replacing total serum cholesterol with anthropometric measures: The MORGAM prospective cohort project.

Victoria Rosberg, Julie Kk Vishram-Nielsen, Anna M Dyrvig Kristensen, Manan Pareek, Thomas S G Sehested, Peter M Nilsson, Allan Linneberg, Luigi Palmieri, Simona Giampaoli, Chiara Donfrancesco and 21 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Preventive medicine reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Victoria RosbergDepartment of Cardiology, North Zealand Hospital, Hillerød, Denmark.
Julie Kk Vishram-NielsenDepartment of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Anna M Dyrvig KristensenDepartment of Cardiology, North Zealand Hospital, Hillerød, Denmark.
Manan PareekDepartment of Cardiology, North Zealand Hospital, Hillerød, Denmark.
Thomas S G SehestedDepartment of Medicine, Zealand University Hospital, Roskilde, Denmark.
Peter M NilssonDepartment for Clinical Sciences Medicine, Lund University, Skane University Hospital, Malmö, Sweden.
Allan LinnebergCenter for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region of Denmark, Copenhagen, Frederiksberg, Denmark.
Luigi PalmieriDepartment of Cardiovascular, Endocrine-metabolic Diseases and Aging, Istituto Superiore di Sanità (ISS), Rome, Italy.
Simona GiampaoliDepartment of Cardiovascular, Endocrine-metabolic Diseases and Aging, Istituto Superiore di Sanità (ISS), Rome, Italy.
Chiara DonfrancescoDepartment of Cardiovascular, Endocrine-metabolic Diseases and Aging, Istituto Superiore di Sanità (ISS), Rome, Italy.
Frank KeeCentre for Public Health, The Queeńs University of Belfast, Northern Ireland.
Giuseppe ManciaUniversity of Milano-Bicocca and Policlinico di Monza, Monza, Italy.
Giancarlo CesanaResearch Centre on Public Health, University of Milano Bicocca, Villa Serena, Monza, Italy.
Giovanni VeronesiResearch Centre in Epidemiology and Preventive Medicine (EPIMED), Department of Medicine and Surgery, University of Insubria, Italy.
Guido GrassiClinica Medica, University Milano Bicocca, Monza, Italy.
Kari KuulasmaaFinnish Institute for Health and Welfare (THL), Helsinki, Finland.
Veikko SalomaaFinnish Institute for Health and Welfare (THL), Helsinki, Finland.
Tarja PalosaariFinnish Institute for Health and Welfare (THL), Helsinki, Finland.
Susana SansCatalan Department of Health, Barcelona, Spain.
Jean FerrieresDepartment of Cardiology, Toulouse University School of Medicine, Rangueil Hospital, Toulouse Cedex 9, France.
Jean DallongevilleInstitut Pasteur de Lille, Lille Cedex, France.
Stefan SöderbergDepartment of Public Health and Clinical Medicine, Cardiology and Heart Centre, Umeå University, Umeå, Sweden.
Marie MoitryDepartment of Epidemiology and Public Health, University of Strasbourg and University Hospital of Strasbourg, Strasbourg, France.
Wojciech DrygasDepartment of Epidemiology, CVD Prevention and Health Promotion, National Institute of Cardiology, Warsaw, Poland.
Abdonas TamosiunasLithuanian University of Health Sciences, Institute of Cardiology, Kaunas, Lithuania.
Annette PetersHelmholtz Zentrum München, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany.
Hermann BrennerGerman Cancer Research Center (DKFZ), Heidelberg, Germany, Network Aging Research (NAR), Heidelberg University, Heidelberg, Germany.
Ben SchöttkerDivision of Clinical Epidemiology and Ageing Research, German Cancer Research Center, Heidelberg, Germany.
Sameline GrimsgaardDepartment of Community Medicine, UiT the Arctic University of Norway, Tromsø, Norway.
Tor Biering-SørensenDepartment of Cardiology, Herlev and Gentofte Hospital, Copenhagen, Denmark.
Michael H OlsenDepartment of Internal Medicine, Steno Diabetes Center Zealand, Holbaek Hospital, Holbaek, Denmark.

Funding

Medical Research Council G0601463Medical Research Council MR/K023241/1
6 · The paper itself

Abstract

To assess whether anthropometric measures (body mass index [BMI], waist-hip ratio [WHR], and estimated fat mass [EFM]) are independently associated with major adverse cardiovascular events (MACE), and to assess their added prognostic value compared with serum total-cholesterol. The study population comprised 109,509 individuals (53% men) from the MORGAM-Project, aged 19-97 years, without established cardiovascular disease, and not on antihypertensive treatment. While BMI was reported in all, WHR and EFM were reported in ∼52,000 participants. Prognostic importance of anthropometric measurements and total-cholesterol was evaluated using adjusted Cox proportional-hazards regression, logistic regression, area under the receiver-operating-characteristic curve (AUC

Indexed as

ACM, all-cause mortalityAdipose tissueASCVD, atherosclerotic cardiovascular diseaseAssessment, riskAUCROC, area under the receiver-operating-characteristic curveBMI, body mass indexBody mass indexBP, blood pressureCardiovascular diseasesCEP, composite cardiovascular endpointCholesterolChol, serum total cholesterolCI, confidence intervalcNRI, continuous net reclassification improvementCV, cardiovascularCVD, cardiovascular diseaseCVM, cardiovascular mortalityDBP, diastolic blood pressureEFM, estimated fat massHDL-cholesterol, high density lipoprotein cholesterolHR, hazard ratioIQR, interquartile rangeMACE, major adverse cardiovascular eventsMBP, mean blood pressureMONICA, Multi-national MONItoring of Trends and Determinants in CArdiovascular DiseaseMORGAM, MOnica, Risk, Genetics, Archiving and MonographNRI, net reclassification improvementNS, non-significantPP, pulse pressureSBP, systolic blood pressureSCORE, Systematic COronary Risk EvaluationWaist-hip ratioWHR, waist-hip ratio

Identifiers

PMID35141116
PMCPMC8814644

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.