ArticleCureus2021
COVID-19 mRNA Vaccination, ABO Blood Type and the Severity of Self-Reported Reactogenicity in a Large Healthcare System: A Brief Report of a Cross-Sectional Study.
Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 12 citations in OpenAlex.
- Impact of ABO Blood System on Immunogenicity and Vaccine Efficacy of COVID-19 Booster Vaccination-A Population-Based Study of 3066 Individuals.Influenza and other respiratory viruses · 2026Article
- Comparison of adverse events following the second/third dose of BNT162b2 in a medical institute in Japan.Heliyon · 2024Article
- Examination of iatrogenic FDG accumulation after COVID-19 vaccination.Annals of nuclear medicine · 2024Article
- Investigating ABO Blood Groups and Secretor Status in Relation to SARS-CoV-2 Infection and COVID-19 Severity.Journal of personalized medicine · 2024Review
- Investigation of the Side Effects of COVID-19 Vaccines in Southern Iran: A Cross-Sectional Study.Archives of Razi Institute · 2024Article
- Observational
- Association between ABO blood groups and the risk of infection with SARS-CoV-2 in Iraq.The Journal of international medical research · 2022Article
- Article
- Real-World Use and Adverse Events of SARS-CoV-2 Vaccination in Greek Patients with Inflammatory Bowel Disease.Journal of clinical medicine · 2022Article
- Assessment of immunoglobin G (spike and nucleocapsid protein) response to COVID-19 vaccination in Palestine.Clinical epidemiology and global healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction It has been anecdotally observed that ABO blood type may have an impact on the severity of the side-effects experienced by those receiving mRNA vaccination for COVID-19. Methods As part of a larger study, a retrospective cross-sectional survey was made available to approximately 33,000 front-line healthcare workers, students and volunteers who were offered voluntary vaccination in a state-wide healthcare system during phase one of the state's vaccine roll-out. A secondary endpoint of the survey was to determine if there was any relationship between vaccination reactogenicity and ABO blood type. Results 4009 responses were received - a 12.15% response rate. 3700 respondents answered the blood type question, and of those, 2878 knew their blood type. By Kruskal-Wallis test, there was no statistically significant association between any blood type and any side effect for either of the COVID-19 mRNA vaccines. Conclusions COVID-19 mRNA vaccination may cause significant reactogenicity. However, ABO blood type does not appear to be a predictor of vaccine reactogenicity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.