Evidence map›Paper›PMID 35140900›Full record

ArticleJournal of healthcare engineering2022

Clinical Study on the Relationship between the SNP rs8192675 (C/C) Site of SLC2A2 Gene and the Hypoglycemic Effect of Metformin in Type 2 Diabetes.

Weiwei Ye, Yi Wang, Feng Chen, Qian Zhao, Xiangying Meng, Jianyang Chen, Cong Liu, Yong Zhou

RetractedOpen access · hybridFull text readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of healthcare engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Weiwei YeDepartment of Endocrinology, Dahua Hospital, Xuhui, Shanghai 200237, China.ORCID 0000-0001-9228-2591
Yi WangDepartment of Endocrinology, Dahua Hospital, Xuhui, Shanghai 200237, China.
Feng ChenDepartment of Endocrinology, Dahua Hospital, Xuhui, Shanghai 200237, China.
Qian ZhaoDepartment of Endocrinology, Dahua Hospital, Xuhui, Shanghai 200237, China.
Xiangying MengDepartment of Endocrinology, Dahua Hospital, Xuhui, Shanghai 200237, China.
Jianyang ChenDepartment of Endocrinology, Dahua Hospital, Xuhui, Shanghai 200237, China.
Cong LiuDepartment of Endocrinology, Dahua Hospital, Xuhui, Shanghai 200237, China.
Yong ZhouDepartment of Endocrinology, Dahua Hospital, Xuhui, Shanghai 200237, China.ORCID 0000-0003-3766-5551
Dahua Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the correlation between the gene polymorphism of rs8192675 (C/C) locus of SLC2A2 in patients with type 2 diabetes (T2DM) and the efficacy of metformin. For this purpose, we have selected 110 T2DM patients (T2DM group) and 110 healthy people (control group) who were treated in our hospital from January 2019 to January 2020 as the research subjects. PCR-restriction fragment length polymorphism (PCR-RFLP) method detects the distribution frequency of gene polymorphism. The patients in the T2DM group were treated with metformin and followed up for 90 days to analyze the relationship between the efficacy of metformin and the SLC2A2 gene polymorphism. The genotypes of SLC2A2 rs8192675 in the control group and in the T2DM group conformed to the Hardy-Weinberg equilibrium law. Compared with the control group, the CT type and the CC type at rs8192675 in the T2DM group were significantly higher (

Indexed as

Diabetes Mellitus, Type 2MetforminGlucose Transporter Type 2Glycated HemoglobinHumansHypoglycemic AgentsPolymorphism, Single NucleotideGlucose Transporter Type 2Glycated HemoglobinHypoglycemic AgentsMetforminSLC2A2 protein, human

Identifiers

PMID35140900
PMCPMC8820847
OpenAlexW4213158245

What OpenQuestion holds

Textfull text, public
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.