Evidence map›Paper›PMID 35140799›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

Antihistaminergic and Anticholinergic Properties of the Root Bark Aqueous Extract of

Vandza Luc Vandi, André Perfusion Amang, Christophe Mezui, Gaël Tchokomeni Siwe, Gustave Lebeau Otto Ndji, Hacheked Mbida, Odile Baponwa, Paul Vernyuy Tan

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Plants (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Vandza Luc VandiDepartment of Biological Sciences, Faculty of Science, University of Maroua, P.O. Box 814, Maroua, Cameroon.
André Perfusion AmangDepartment of Biological Sciences, Faculty of Science, University of Maroua, P.O. Box 814, Maroua, Cameroon.ORCID https://orcid.org/0000-0002-5331-720X
Christophe MezuiDepartment of Biological Sciences, Higher Teachers' Training College, University of Yaoundé I, P.O. Box 047, Yaoundé, Cameroon.
Gaël Tchokomeni SiweDepartment of Animal Biology and Physiology, Faculty of Science, University of Yaoundé I, P.O. Box 812, Yaoundé, Cameroon.ORCID https://orcid.org/0000-0002-1771-1939
Gustave Lebeau Otto NdjiDepartment of Life Science, Higher Teachers' Training College, University of Ngaoundéré, P.O. Box 652, Bertoua, Cameroon.
Hacheked MbidaDepartment of Biological Sciences, Faculty of Science, University of Maroua, P.O. Box 814, Maroua, Cameroon.
Odile BaponwaDepartment of Biological Sciences, Faculty of Science, University of Maroua, P.O. Box 814, Maroua, Cameroon.
Paul Vernyuy TanDepartment of Animal Biology and Physiology, Faculty of Science, University of Yaoundé I, P.O. Box 812, Yaoundé, Cameroon.ORCID https://orcid.org/0000-0002-5258-1412
University of Maroua · CMUniversité de Yaoundé I · CMUniversity of Ngaoundéré · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective of this study was to elucidate the antisecretory mechanism of the root bark aqueous extract of

resultsIn the three models studied, RBAEDM resulted in increases in the percentages of inhibition ranging from 9.50 to 59.52% of gastric ulcer and mucus mass. This increase was accompanied by the reduction in acidity and pepsin activity. The administration of RBAEDM resulted in a significant decrease (

conclusionRBAEDM protected gastric mucous membrane for gastric acid by mechanisms that would involve both anticholinergic and antihistaminergic pathways.

Identifiers

PMID35140799
PMCPMC8820865
OpenAlexW4210543823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.