ArticleJournal of inflammation research2022
Nonlinear Relationship Between Chinese Visceral Adiposity Index and New-Onset Myocardial Infarction in Patients with Hypertension and Obstructive Sleep Apnoea: Insights from a Cohort Study.
Article in Journal of inflammation research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Composite lipid indices in patients with obstructive sleep apnea: a systematic review and meta-analysis.Lipids in health and disease · 2023Pooled it
- The role of visceral obesity surrogate markers in predicting cardiovascular disease: Insights from the CHARLS study.Medicine · 2026Article
- Assessment of seven insulin resistance surrogate indexes for predicting cardiometabolic multimorbidity among Chinese middle-aged and older adults: a national prospective cohort study.Cardiovascular diabetology · 2026Article
- The body mass index-glucose index as a new tool for early detection of the risk of dysglycemia in patients with hypertension and obstructive sleep apnea.BMC endocrine disorders · 2026Article
- Quantitative CT analysis of intra-abdominal fat, subcutaneous fat, and bone mineral density disparities in individuals with obesity and obstructive sleep apnea compared to those with obesity alone.Head & face medicine · 2026Article
- Development and validation of a nomogram model to predict coronary heart disease in snoring patients with hypertension and non-glucose metabolism disorders.Journal of medical biochemistry · 2025Article
- Comparative analysis of 16 baseline obesity and lipid-related indices for cardiovascular disease risk prediction in adults with cardiovascular-kidney-metabolic syndrome stages 0-3: a nationwide prospective cohort study.Diabetology & metabolic syndrome · 2025Article
- Association of CVAI with BMD, FRAX scores, and osteoporosis risk in Chinese elderly patients with hypertension.Scientific reports · 2025Article
- Association between Chinese visceral adiposity index and cardiovascular events risk in individuals with cardiovascular-kidney-metabolic syndrome stage 0-3: a nationwide cohort study.International urology and nephrology · 2025Article
- Clinical significance of obesity measurement indicators and carotid artery plaques in type 2 diabetes.BMC cardiovascular disorders · 2025Article
- Chinese Guidelines for the Prevention and Treatment of Hypertension (2024 revision).Journal of geriatric cardiology : JGC · 2025Article
- The association between lipid-related obesity indicators and severe headache or migraine: a nationwide cross sectional study from NHANES 1999 to 2004.Lipids in health and disease · 2025Article
- Association Between the Chinese Visceral Adiposity Index and Obstructive Sleep Apnoea in Hypertensive Patients with Normal-Weight: A Cross-Sectional Study.International journal of general medicine · 2025Article
- Exploring the Relationship Between Sleep Apnea, Myocardial Infarct Size, and Coronary Collaterals in Acute Myocardial Infarction: A Multidisciplinary Study.Nature and science of sleep · 2025Article
- Correlation between Chinese visceral adiposity index and serum uric acid levels in type 2 diabetes mellitus patients.Frontiers in endocrinology · 2025Article
- Association of Metabolic Score for Visceral Fat (METS-VF) with Gout Risk in Patients with Hypertension and Hyperuricemia: A Multicenter Study Based on the Chinese Population.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Association of visceral adiposity index and lipid accumulation product with frailty in U.S. adults: a cross-sectional study from NHANES.Lipids in health and disease · 2024Article
- Neck circumference, waist-to-height ratio, Chinese visceral adiposity index and incident heart failure.Nutrition journal · 2024Article
- Association between obstructive sleep apnea and 24-h urine protein quantification in patients with hypertension.Scientific reports · 2024Article
- Chinese visceral adipose index is more closely associated with risk of arterial stiffness than traditional obesity indicators: a cohort study.Diabetology & metabolic syndrome · 2024Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe aimed to investigate the relationship between the Chinese visceral adiposity index (CVAI) and the risk of new-onset myocardial infarction (MI) in patients with hypertension and obstructive sleep apnoea (OSA) and to inspect possible modifiers of the effect.
methodsThe Cox regression model was used to evaluate the relationship between baseline CVAI and risk of new-onset MI. A generalized additive model was used to identify the nonlinear relationship. Besides, we conducted subgroup analyses and interaction tests.
resultsA total of 2177 patients with hypertension and OSA undergoing polysomnography were enrolled in this study. During a median follow-up period of 87 months, 82 participants developed new-onset MI. Overall, CVAI was positively related to the risk of new-onset MI (per 1 SD increase; HR = 1.54, 95% CI: 1.28-1.85). In multivariable-adjusted models, the risk of new-onset MI increased with quartiles of CVAI, with an HR of 3.64 (95% CI: 1.94-6.83) for quartile 4 compared with quartile 1. The generalized additive model and smoothed curve fit revealed a nonlinear relationship between CVAI and risk of new-onset MI with an inflection point of approximately 112. None of the stratification variables had a significant effect on the relationship between CVAI and new-onset MI. Similar outcomes were observed in the sensitivity analysis. The addition of CVAI significantly improved reclassification and discrimination over the conventional model, with a category-free NRI of 0.132 (95% CI 0.021 to 0.236, P = 0.021) and an IDI of 0.012 (95% CI 0.005 to 0.023, P < 0.001).
conclusionThis study demonstrated a nonlinear relationship between CVAI and the risk of new-onset MI in patients with hypertension and OSA. Higher CVAI was significantly associated with the risk of new-onset MI when CVAI was ≥112.
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