Evidence map›Paper›PMID 35140465›Full record

ArticleNeuropsychiatric disease and treatment2022

Lack of Association of

Ming Gao, Haisheng Lin, Bingxiao Li, Junjie Wen, Yingying Wang, Zhanhui Zhang, Wenxiong Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuropsychiatric disease and treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ming GaoDepartment of Neurology, First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, 510630, People's Republic of China.
Haisheng LinDepartment of Neurology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, 510120, People's Republic of China.
Bingxiao LiDepartment of Pediatrics, First Affiliated Hospital, Jinan University, Guangzhou, Guangdong, 510630, People's Republic of China.
Junjie WenDepartment of Pediatrics, First Affiliated Hospital, Jinan University, Guangzhou, Guangdong, 510630, People's Republic of China.ORCID 0000-0002-8377-8066
Yingying WangDepartment of Neurology, First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, 510630, People's Republic of China.
Zhanhui Zhang *Clinical Medicine Research Institute, First Affiliated Hospital, Jinan University, Guangzhou, 510630, People's Republic of China.
Wenxiong Chen *Department of Neurology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, 510120, People's Republic of China.
First Affiliated Hospital of Jinan University · CNGuangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTic disorders (TDs) are highly polygenic and heritable neurodevelopmental disorders characterized by the presence of movements (motor tics) and/or vocalizations (phonic tics).

methodsA total of 116 child TD patients and 114 healthy controls were included. All children underwent peripheral blood sampling for genomic DNA extraction. Gene fragments with two single-nucleotide polymorphisms were amplified by PCR and sequenced by Sanger chain termination before genotype analysis.

results

conclusionOur results provide no evidence to support the previous conclusion that

Indexed as

FLT3Fms related receptor tyrosine kinase 3SLIT and NTRK like family member 1SLITRK1tic disordersTourette's syndrome

Identifiers

PMID35140465
PMCPMC8818983
OpenAlexW4210288099

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.