Evidence map›Paper›PMID 35140172›Full record

ArticleRNA (New York, N.Y.)2022

Yeast Dxo1 is required for 25S rRNA maturation and acts as a transcriptome-wide distributive exonuclease.

Jennifer E Hurtig, Ambro van Hoof

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RNA (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jennifer E HurtigMicrobiology and Molecular Genetics, University of Texas Health Science Center, Houston, Texas 77030, USA.
Ambro van HoofMicrobiology and Molecular Genetics, University of Texas Health Science Center, Houston, Texas 77030, USA.
The University of Texas Health Science Center at Houston · US

Funding

RNAse functions in post-transcriptional gene regulationR35GM141710 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI VAN HOOF, AMBRO · 2021 to 2025
$2.4M
Insight Into The RNA Processing And Decay Pathways Critical For Proper Neuronal Development And Function Through Focus On Mutations That Cause Pontocerebellar HypoplasiaR01GM130147 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI CORBETT, ANITA H., VAN HOOF, AMBRO · 2018 to 2021
$1.4M
NIGMS NIH HHS R01 GM130147NIGMS NIH HHS R35 GM141710
6 · The paper itself

Abstract

The Dxo1/Rai1/DXO family of decapping and exonuclease enzymes can catalyze the in vitro removal of chemically diverse 5' ends from RNA. Specifically, these enzymes act poorly on RNAs with a canonical

Indexed as

Saccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsExonucleasesExoribonucleasesNuclear ProteinsRNARNA-Binding ProteinsRNA, RibosomalTranscriptomeExonucleasesExoribonucleasesNuclear ProteinsRai1 protein, S cerevisiaeRAT1 protein, S cerevisiaeRNARNA-Binding ProteinsRNA, RibosomalRNA, ribosomal, 25SSaccharomyces cerevisiae Proteins5′ exoribonucleasedegradomerRNA processing

Identifiers

PMID35140172
PMCPMC9014881
OpenAlexW4210915979

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.