Evidence map›Paper›PMID 35140089›Full record

ArticleBMJ case reports2022

A possible Guillain-Barré syndrome/transverse myelitis overlap syndrome after recent COVID-19.

Riyadh Alrubaye, Vijayamala Bondugula, Vidya Baleguli, Rosemary Chofor

Open access · hybridAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Riyadh AlrubayeDepartment of Hospital Medicine/Internal Medicine Residency Program, Northeast Georgia Health System Inc, Gainesville, Georgia, USA ralrubaye@gmail.com.
Vijayamala BondugulaDepartment of Neurology, Northeast Georgia Health System Inc, Gainesville, Georgia, USA.
Vidya BaleguliDepartment of GME/Internal Medicine, Northeast Georgia Health System Inc, Gainesville, Georgia, USA.
Rosemary ChoforDepartment of GME/Internal Medicine Residency Program, Northeast Georgia Health System Inc, Gainesville, Georgia, USA.
Southeast Georgia Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurological manifestations are common in SARS-CoV-2 infection, including life-threatening acute muscle weakness, due to neuromuscular disorders such as acute transverse myelitis (TM) and Guillain-Barré syndrome (GBS). These syndromes can rarely coexist and present as an overlap syndrome. Here, we report a patient who developed acute symmetrical proximal lower limb weakness 5 days after diagnosis of COVID-19. GBS was diagnosed due to the presence of motor signs, albumin-cytological dissociation in cerebrospinal fluid examination and axonal damage according to nerve condition tests. However, abnormal areas on MRI of the thoracic spine and lack of improvement with intravenous immunoglobulin supported a diagnosis of TM. Therefore, a possible overlap between GBS and TM was established. To our knowledge, this is the third case report of GBS/TM overlap syndrome after COVID-19. The patient's full and rapid recovery with intravenous corticosteroids and plasmapheresis supports our diagnosis.

Indexed as

Autoimmune DiseasesCOVID-19Guillain-Barre SyndromeMyelitis, TransverseHumansSARS-CoV-2COVID-19infection (neurology)neuroimagingneuromuscular diseasespinal cord

Identifiers

PMID35140089
PMCPMC8830199
OpenAlexW4210840450

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.