Evidence map›Paper›PMID 35139865›Full record

ArticleActa veterinaria Scandinavica2022

Characterisation of and risk factors for extended-spectrum β-lactamase producing Enterobacterales (ESBL-E) in an equine hospital with a special reference to an outbreak caused by Klebsiella pneumoniae ST307:CTX-M-1.

Katariina Thomson, Katarina Eskola, Marjut Eklund, Kristiina Suominen, Merita Määttä, Jouni Junnila, Suvi Nykäsenoja, Kati Niinistö, Thomas Grönthal, Merja Rantala

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta veterinaria Scandinavica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Katariina Thomson *Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, PO Box 57, 00014, Helsinki, Finland. katariina.thomson@helsinki.fi.ORCID http://orcid.org/0000-0001-5863-037X
Katarina Eskola *Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, PO Box 57, 00014, Helsinki, Finland.
Marjut EklundDepartment of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, PO Box 57, 00014, Helsinki, Finland.
Kristiina SuominenDepartment of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, PO Box 66, 00014, Helsinki, Finland.
Merita MäättäDepartment of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, PO Box 57, 00014, Helsinki, Finland.
Jouni JunnilaOy 4Pharma Ltd, Arkadiankatu 7, 00100, Helsinki, Finland.
Suvi NykäsenojaFinnish Food Authority, PO Box 100, 00027, Helsinki, Finland.
Kati NiinistöVeterinary Teaching Hospital, Faculty of Veterinary Medicine, University of Helsinki, PO Box 57, 00014, Helsinki, Finland.
Thomas GrönthalDepartment of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, PO Box 57, 00014, Helsinki, Finland.
Merja RantalaDepartment of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, PO Box 57, 00014, Helsinki, Finland.
University of Helsinki · FIFinnish Food Authority · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExtended-spectrum β-lactamase producing Enterobacterales (ESBL-E) are important causative agents for infections in humans and animals. At the Equine Veterinary Teaching Hospital of the University of Helsinki, the first infections caused by ESBL-E were observed at the end of 2011 leading to enhanced infection surveillance. Contact patients were screened for ESBL-E by culturing infection sites and rectal screening. This study was focused on describing the epidemiology and microbiological characteristics of ESBL-E from equine patients of the EVTH during 2011-2014, and analysing putative risk factors for being positive for ESBL-E during an outbreak of Klebsiella pneumoniae ST307.

resultsThe number of ESBL-E isolations increased through 2012-2013 culminating in an outbreak of multi-drug resistant K. pneumoniae ST307:bla

conclusionsThe occurrence of an outbreak caused by a pathogenic ESBL-producing K. pneumoniae ST307 strain highlights the importance of epidemiological surveillance of ESBL-E in veterinary hospitals. Limiting the length of hospitalisation for equine patients may reduce the risk of spread of ESBL-E. It is also important to acknowledge the importance of nasogastric tubing as a potential source of acquiring ESBL-E. As ESBL-E were also found in stomach drench pumps used with nasogastric tubes, veterinary practices should pay close attention to appropriate equipment cleaning procedures and disinfection practices.

Indexed as

Horse DiseasesKlebsiella InfectionsAnimalsAnti-Bacterial Agentsbeta-LactamasesDisease OutbreaksFemaleHorsesHospitals, AnimalHospitals, TeachingHumansKlebsiella pneumoniaeMicrobial Sensitivity TestsRisk FactorsAnti-Bacterial Agentsbeta-Lactamasesbeta-lactamase TEM-3Bacterial infectionClusterHorseMulti-drug resistant bacteriaNosocomial infectionSurveillance

Identifiers

PMID35139865
PMCPMC8827190
OpenAlexW4210907135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.