Evidence map›Paper›PMID 35139854›Full record

ArticleBMC musculoskeletal disorders2022

Surgical treatment, complications, reoperations, and healthcare costs among patients with clavicle fracture in England.

Simone Wolf, Abhishek S Chitnis, Anandan Manoranjith, Mollie Vanderkarr, Javier Quintana Plaza, Laura V Gador, Chantal E Holy, Charisse Sparks, Simon M Lambert

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Clavicular bone defects managed with free vascularised fibular grafting: evidence to date.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023
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  15. [Effectiveness of minimally invasive internal fixation with locking plates for mid-shaft clavicle fractures].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Simone WolfSynthes GmbH, Zuchwil, Switzerland.
Abhishek S ChitnisMedical Devices Epidemiology, Johnson & Johnson, New Brunswick, NJ, USA.
Anandan ManoranjithMu Sigma, Bangalore, India.
Mollie VanderkarrDePuy Synthes, Inc., West Chester, PA, USA.
Javier Quintana PlazaJohnson and Johnson, Madrid, Spain.
Laura V GadorJohnson and Johnson GmbH, Neuss, Germany.
Chantal E HolyMedical Devices Epidemiology, Johnson & Johnson, New Brunswick, NJ, USA. choly1@its.jnj.com.
Charisse SparksDePuy Synthes, Inc., West Chester, PA, USA.
Simon M LambertUniversity College London Hospital, London, UK.
Johnson & Johnson (United States) · USJohnson & Johnson (Germany) · DESynthena (Switzerland) · CHUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe clinical and economic burden of clavicle fractures in England is not well documented. This study evaluated rates of surgical treatment, post-surgical complications, reoperations and costs in patients with clavicle fractures using the Clinical Practice Research Datalink (CPRD) database.

methodsCPRD data were linked to National Health Service Hospital Episode Statistics data. Patients with a diagnosis of clavicle fracture between 2010-2018 were selected in CPRD (date of fracture = index date). Of those, patients with surgical intervention within 180 days from index fracture were identified. Rates of post-surgical complications (i.e., infection, non-union, and mal-union), reoperations (for device removal or for postoperative complications), post-operative costs and median time to reoperations were evaluated up to 2 years after surgery.

results21,340 patients with clavicle fractures were identified (mean age 35.0 years(standard deviation (SD): 26.5), 66.7% male). Surgery was performed on 672 patients (3.2% of total cohort) at an average 17.1 (SD: 25.2) days post-fracture. Complications (i.e., infection, non-union, or malunion) affected 8.1% of surgically treated clavicle fracture patients; the rate of infection was 3.5% (95% CI, 1.7%- 5.2%), non-union 4.4% (95% CI, 2.4%-6.5%), and mal-union 0.3% (95% CI, 0%-0.7%). Adjusting for age, gender, comorbidities and time to surgery, the all-cause reoperation rate was 20.2% (13.2%-30.0%) and the adjusted rate of reoperation for implant removal was 17.0% (10.7%-25.9%)-84% of all-cause reoperations were thus performed for implant removal. Median time to implant removal was 254 days. The mean cost of reoperations for all causes was £5,000. The most expensive reoperations were for cases that involved infection (mean £6,156).

conclusionsComplication rates following surgical clavicle fracture care averaged 8.1%. However, reoperation rates exceed 20%, the vast majority of reoperations being performed for device removal. Technologies to alleviate secondary device removal surgeries would address a significant clinical unmet need.

Indexed as

ClavicleFractures, BoneAdultBone PlatesFemaleFracture Fixation, InternalHealth Care CostsHumansMaleReoperationRetrospective StudiesState MedicineTreatment OutcomeClavicleCohort StudiesCost of IllnessFractures, BonePostoperative ComplicationsReoperationUnited Kingdom

Identifiers

PMID35139854
PMCPMC8830003
OpenAlexW4210905550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.