Evidence map›Paper›PMID 35139773›Full record

ArticleBioengineered2022

Methyltransferase-like (METTL)14-mediated N6-methyladenosine modification modulates retinal pigment epithelial (RPE) activity by regulating the methylation of microtubule-associated protein (MAP)2.

Lu Yin, Cong Ma, Shengping Hou, Xiang Ma

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. WTAP mediated mScience China. Life sciences · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. mEpigenetics · 2023
    Article
  11. Review
  12. Article
  13. From Bench to Bed: The Current Genome Editing Therapies for Glaucoma.Frontiers in cell and developmental biology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Lu YinDepartment of Ophthalmology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.ORCID 0000-0002-1492-3071
Cong MaThe First Affiliated Hospital of Dalian Medical University, Dalian, China.
Shengping HouThe First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xiang MaDepartment of Ophthalmology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Dalian Medical University · CNChongqing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The expression of METTL14 is significantly reduced in patients with retinitis pigmentosa (RP). To clarify the significance of the N6-methyladenosine (m

Indexed as

MethyltransferasesMicrotubule-Associated ProteinsRetinal Pigment EpitheliumAdenosineHumansMethylationRNAAdenosineMAP2 protein, humanMethyltransferasesMETTL14 protein, humanMicrotubule-Associated ProteinsN-methyladenosineRNAm6AMAP2METTL14NEUROD1retinal pigment epithelial cellsretinitis pigmentosaRNA methylationYTHDF2

Identifiers

PMID35139773
PMCPMC8973965
OpenAlexW4211240551

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.