Evidence map›Paper›PMID 35139769›Full record

ArticleBioengineered2022

Long noncoding RNA H19 suppresses cardiac hypertrophy through the MicroRNA-145-3p/SMAD4 axis.

Hao Wang, Xiaoqing Lian, Wei Gao, Jie Gu, Haojie Shi, Yao Ma, Yafei Li, Yi Fan, Qiming Wang, Liansheng Wang

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. The Role of Stem Cells in the Treatment of Cardiovascular Diseases.International journal of molecular sciences · 2024
    Review
  3. Review
  4. Review
  5. Noncoding RNAs as Key Regulators for Cardiac Development and Cardiovascular Diseases.Journal of cardiovascular development and disease · 2023
    Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hao WangDepartment of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xiaoqing LianDepartment of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Wei GaoDepartment of Geriatrics, Sir Run Run Hospital of Nanjing Medical University, Nanjing, China.
Jie GuDepartment of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Haojie ShiDepartment of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yao MaDepartment of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yafei LiDepartment of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yi FanDepartment of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Qiming WangDepartment of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Liansheng WangDepartment of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jiangsu Province Hospital · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sustained cardiac hypertrophy (CH) contributes to many heart diseases. Long noncoding RNAs (lncRNAs) collectively play critical roles in cardiovascular diseases (CVDs). However, the roles of lncRNA H19 in CH are still unclear. A CH model was constructed utilizing isoproterenol (ISO). We demonstrated H19 could participate in regulating ISO-induced CH development both

Indexed as

CardiomegalyMicroRNAsRNA, Long NoncodingSmad4 ProteinAnimalsAtrial Natriuretic FactorMiceMice, KnockoutStroke VolumeVentricular Function, LeftAtrial Natriuretic FactorH19 long non-coding RNAMicroRNAsMIRN145a microRNA, mouseRNA, Long NoncodingSmad4 ProteinSmad4 protein, mouseCardiac hypertrophy (ch)h19miR-145-3pmolecular mechanismsmad4

Identifiers

PMID35139769
PMCPMC8973863
OpenAlexW4211195687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.