Evidence map›Paper›PMID 35139574›Full record

Trial reportRevista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia2022

Prevention of Premature Ovulation by Administration of Gonadotropin Releasing Hormone Antagonist the day After Ovulation Triggering in Diminished Ovarian Reserve Patients.

Bulat Aytek Sik, Ozan Ozolcay, Yilda Arzu Aba, Alper Sismanoglu, Sifa Savas, Serkan Oral

Open access · diamondAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Bulat Aytek SikDepartment of Reproductive Endocrinology and Infertility, Sisli Kolan International Hospital, Istanbul, Turkey.ORCID 0000-0002-4165-9405
Ozan OzolcayDepartment of Reproductive Endocrinology and Infertility, Istanbul IVF Centre, Istanbul, Turkey.ORCID 0000-0002-9416-6153
Yilda Arzu AbaFaculty of Health Sciences, Bandirma Onyedi Eylül University, Balıkesir, Turkey.ORCID 0000-0001-6660-4964
Alper SismanogluDepartment of Reproductive Endocrinology and Infertility, Sisli Kolan International Hospital, Istanbul, Turkey.ORCID 0000-0003-2895-575X
Sifa SavasDepartment of Reproductive Endocrinology and Infertility, Istanbul IVF Centre, Istanbul, Turkey.ORCID 0000-0001-8750-8955
Serkan OralDepartment of Reproductive Endocrinology and Infertility, Sisli Kolan International Hospital, Istanbul, Turkey.ORCID 0000-0002-1311-6278
Memorial Sisli Hospital · TRIstanbul Memorial Hospital · TRBandırma Onyedi Eylül University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of the present retrospective study was to investigate the effectiveness of single-dose gonadotropin releasing hormone (GnRH) antagonist administration, the day after human chorionic gonadotropin (hCG) triggering for final oocyte maturation, on the prevention of premature luteinization in patients with diminished ovarian reserve in in-vitro fertilization (IVF) cycles. The secondary objective of the study was to search the effect of this protocol on pregnancy outcomes.

methodsThis is a retrospective study including 267 infertile patients who have single antral follicle seen with ultrasonography on the 2

resultsThe premature ovulation rate was significantly low in the case group compared with the control group (6.86 versus 20.6% per scheduled cycle) (

conclusionThe administration of GnRH antagonist the day after hCG trigger in IVF treatments of patients with diminished ovarian reserve enabled a significant decrease in the rate of premature ovulation but had no effect on live birth rate.

Indexed as

Ovarian DiseasesOvarian Hyperstimulation SyndromeOvarian ReservePremature BirthChorionic GonadotropinFemaleFertilization in VitroGonadotropin-Releasing HormoneHormone AntagonistsHumansOvulationOvulation InductionPregnancyPregnancy RateRetrospective StudiesChorionic GonadotropinGonadotropin-Releasing HormoneHormone Antagonists

Identifiers

PMID35139574
PMCPMC9948117
OpenAlexW4211137473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.