SynthesisPloS one2022
The burden of perioperative hypertension/hypotension: A systematic review.
Synthesis in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.
- Risk factors for postoperative acute kidney injury in colorectal cancer: a systematic review and meta-analysis.International journal of colorectal disease · 2025Pooled it
- Effect of multimodal opioid-sparing anesthesia on intestinal function and prognosis of elderly patients with hypertension after colorectal cancer surgery.BMC surgery · 2024Trial
- Association of hypotension burden calculated from intermittently documented blood pressures and outcome after pediatric cardiac arrest.Resuscitation · 2026Article
- Magnesium Sulfate as a Multimodal Anesthetic Adjuvant in Brain Tumor Surgery: A Systematic Review and Meta-Analysis of Hemodynamic, Analgesic, and Biomarker Outcomes.Journal of clinical medicine · 2026Review
- Patient-, Clinician-, and Institution-level Variation in Intraoperative Antihypertensive Use: A Multicenter Observational Analysis.Journal of cardiothoracic and vascular anesthesia · 2026Observational
- Article
- Investigating the potential of the isometric handgrip exercise as a test of cardiovascular reactivity to blood pressure fluctuations.BMC anesthesiology · 2026Observational
- Intravenous adrenaline during general anaesthesia: incidence and adverse events over 11 years.BMC anesthesiology · 2026Article
- Effect of Antihypertensive Treatment on Hypotension, Mortality and Length of Stay in Orthopedic Trauma and First Detected High Blood Pressure Adults in a Large Urban Hospital: A Retrospective Cohort Study.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- The Japanese Society of Hypertension Guidelines for the management of elevated blood pressure and hypertension 2025 (JSH2025).Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Associated Factors of Pre-Anesthesia Blood Pressure Elevation in Elective Non-Cardiac Surgical Patients: A Case-Control Study Comparing Two Diagnostic Thresholds.Risk management and healthcare policy · 2026Article
- Systematic review of the impact of digital health technologies on blood pressure control and treatment adherence in young and middle-aged hypertensive patients.Frontiers in cardiovascular medicine · 2026Review
- Identifying patterns of high intraoperative blood pressure variability in noncardiac surgery using explainable machine learning: a retrospective cohort study.Annals of medicine · 2025Article
- Myocardial Injury and Postoperative Hypotension in the Recovery Room Are Not Correlated: A Retrospective Cohort Study.Journal of clinical medicine · 2025Article
- Comparison of Two Initial Effect-Site Concentrations of Remifentanil with Propofol During Percutaneous Vertebroplasty Under Monitored Anesthesia Care: A Randomized Controlled Study with Titration-Based Adjustment.Journal of clinical medicine · 2025Article
- Correlation of intraoperative blood pressure variability and postoperative delirium in elderly hip fracture surgery.Scientific reports · 2025Article
- Article
- Prolonged alpha-blockade and doxazosin are associated with hypertensive crisis in pheochromocytoma surgery.Frontiers in endocrinology · 2025Article
- Perioperative Blood Pressure Optimization to Improve Outcomes in Orthopedic Patients: A Clinical Review.Therapeutics and clinical risk management · 2025Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectiveOur goal is to review the outcomes of acute hypertensive/hypotensive episodes from articles published in the past 10 years that assessed the short- and long-term impact of acute hypertensive/hypotensive episodes in the perioperative setting.
methodsWe conducted a systematic peer review based upon PROSPERO and Cochrane Handbook protocols. The following study characteristics were collected: study type, author, year, population, sample size, their definition of acute hypertension, hypotension or other measures, and outcomes (probabilities, odds ratio, hazard ratio, and relative risk) and the p-values; and they were classified according to the type of surgery (cardiac and non-cardiac).
resultsA total of 3,680 articles were identified, and 66 articles fulfilled the criteria for data extraction. For the perioperative setting, the number of articles varies by outcome: 20 mortality, 16 renal outcomes, 6 stroke, 7 delirium and 34 other outcomes. Hypotension was reported to be associated with mortality (OR 1.02-20.826) as well as changes from the patient's baseline blood pressure (BP) (OR 1.02-1.36); hypotension also had a role in the development of acute kidney injury (AKI) (OR 1.03-14.11). Postsurgical delirium was found in relation with BP lability (OR 1.018-1.038) and intra- and postsurgical hypotension (OR 1.05-1.22), and hypertension (OR 1.44-2.34). Increased OR (37.67) of intracranial hemorrhage was associated to postsurgical systolic BP >130 mmHg. There was a wide range of additional diverse outcomes related to hypo-, hypertension and BP lability.
conclusionsThe perioperative management of BP influences short- and long-term effects of surgical procedures in cardiac and non-cardiac interventions; these findings support the burden of BP fluctuations in this setting.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.