Evidence map›Paper›PMID 35138938›Full record

ArticleThe British journal of radiology2022

Ultrasound-based radiomics nomogram for differentiation of triple-negative breast cancer from fibroadenoma.

Yu Du, Hai-Ling Zha, Hui Wang, Xin-Pei Liu, Jia-Zhen Pan, Li-Wen Du, Meng-Jun Cai, Min Zong, Cui-Ying Li

Abstract read
In one paragraph

Article in The British journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yu DuDepartment of Ultrasound, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Hai-Ling ZhaDepartment of Ultrasound, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Hui WangDepartment of Ultrasound, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xin-Pei LiuDepartment of Ultrasound, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jia-Zhen PanDepartment of Ultrasound, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Li-Wen DuDepartment of Ultrasound, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Meng-Jun CaiDepartment of Ultrasound, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Min ZongDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Cui-Ying LiDepartment of Ultrasound, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to develop a radiomics nomogram that incorporates radiomics, conventional ultrasound (US) and clinical features in order to differentiate triple-negative breast cancer (TNBC) from fibroadenoma.

methodsA total of 182 pathology-proven fibroadenomas and 178 pathology-proven TNBCs, which underwent preoperative US examination, were involved and randomly divided into training (

resultsThe radiomics signature, composed of 12 selected features, achieved good diagnostic performance. The nomogram incorporated with radiomics signature and clinical data showed favorable diagnostic efficacy in the training cohort (AUC 0.986, 95% CI, 0.975-0.997) and validation cohort (AUC 0.977, 95% CI, 0.953-1.000). The radiomics nomogram outperformed the Rad-score and clinical models (

conclusionThe radiomics signature is a potential predictive indicator for differentiating TNBC and fibroadenoma. The radiomics nomogram associated with Rad-score, US conventional features, and clinical data outperformed the Rad-score and clinical models. ADVANCES IN KNOWLEDGE: Recent advances in radiomics-based US are increasingly showing potential for improved diagnosis, assessment of therapeutic response and disease prediction in oncology. Rad-score is an independent predictive indicator for differentiating TNBC and fibroadenoma. The radiomics nomogram associated with Rad-score, US conventional features, and clinical data outperformed the Rad-score and clinical models.

Indexed as

FibroadenomaTriple Negative Breast NeoplasmsAlgorithmsHumansNomogramsUltrasonography

Identifiers

PMID35138938
PMCPMC10993963

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.