Evidence map›Paper›PMID 35138914›Full record

ArticleThe British journal of radiology2022

Contrast-enhanced ultrasound features predict the prognosis of percutaneous microwave ablation of intrahepatic cholangiocarcinoma.

Xiaohui Wang, Ping Liang, Jie Yu, Jun-Dong Yao, Fang-Ying Fan, Xiaoling Yu, Zhi-Gang Cheng, Zhi-Yu Han, Fang-Yi Liu, Jian-Ping Dou

Open access · greenAbstract read
In one paragraph

Article in The British journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Radiological Loco-Regional Treatments for Cholangiocarcinoma: A Systematic Review of the Literature.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Pooled it
  2. Review
  3. [Establishment of a database for liver cancer ablation and its clinical research value].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Xiaohui WangDepartment of Interventional Ultrasound, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Ping LiangDepartment of Interventional Ultrasound, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Jie YuDepartment of Interventional Ultrasound, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Jun-Dong YaoDepartment of Interventional Ultrasound, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Fang-Ying FanDepartment of Interventional Ultrasound, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Xiaoling YuDepartment of Interventional Ultrasound, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Zhi-Gang ChengDepartment of Interventional Ultrasound, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Zhi-Yu HanDepartment of Interventional Ultrasound, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Fang-Yi LiuDepartment of Interventional Ultrasound, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Jian-Ping DouDepartment of Interventional Ultrasound, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Chinese PLA General Hospital · CNFirst Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the prognostic effect of pre-operative contrast-enhanced ultrasound (CEUS) features on intrahepatic cholangiocarcinoma (ICC) after percutaneous microwave ablation (MWA).

methodsA total of ICC 29 patients (average age 56.34 ± 9.78 years old, 33~75 years old) underwent MWA from March 2012 to December 2020, with a total of 58 lesions (0.5-8.1 cm, mean diameter, 2.68 ± 1.59 cm), and their pre-operative CEUS images and clinical data were collected and reviewed. Survival rate, local progression rate, intra- and extrahepatic metastasis rate were evaluated. Uni- and multivariate analysis were used to analyze the prognostic factors affecting the survival of ICC patients with pre-operative CEUS features.

resultsThe median follow-up time after MWA was 18.43 months (4.17-93.13 months). 1-, 2-, and 3-year OS rates were 64.4%, 48.1% and 48.1%; 6-, 12-, 18-, 24-, 36-, 48-, and 60-month local progress and extrahepatic metastasis rates were 0.0%, 4.0%, 17.7%, 17.7%, 17.7%, 17.7%, 17.7% and 3.4%, 21.5%, 32.7%, 45.6%, 55.2%, 55.2% and 77.6%, respectively. Uni- and multivariate analysis showed that post-operative extrahepatic metastasis was an important factor for long-term survival of ICC patients after MWA (

conclusionRim-enhancement feature of pre-operative CEUS is a predictor high post-operative extrahepatic metastasis and poor prognosis through distant microvascular metastasis after MWA of ICC patients. ADVANCES IN KNOWLEDGE: This study determined the important CEUS features of ICC and analyzed their impact on the prognosis of ICC patients after MWA, providing scientific guidance for better clinical treatment in the future.

Indexed as

Bile Duct NeoplasmsCatheter AblationCholangiocarcinomaLiver NeoplasmsAgedBile Ducts, IntrahepaticHumansMicrowavesMiddle AgedPrognosisRetrospective Studies

Identifiers

PMID35138914
PMCPMC10993967
OpenAlexW4210915228

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.