ArticleAdvances in experimental medicine and biology2021
The Role of Thermosensitive Ion Channels in Mammalian Thermoregulation.
Article in Advances in experimental medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 4 citations in OpenAlex.
- Heat acclimation defense against exertional heat stroke by improving the function of preoptic TRPV1 neurons.Theranostics · 2025Article
- The influence of temperature and genomic variation on intracranial EEG measures in people with epilepsy.Brain communications · 2024Article
- Intercellular Calcium Waves and Permeability Change Induced by Vertically Deployed Surface Acoustic Waves in a Human Cerebral Microvascular Endothelial Cell Line (hCMEC/D3) Monolayer.Ultrasound in medicine & biology · 2023Article
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2 authors at 1 institution in 1 country.
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Abstract
Ambient temperature detection and core body temperature maintenance are critical for the environment adaptability of mammals, requiring an elaborate neural network that converts the temperature information sensed by thermoreceptors into physiological and behavioral thermoregulatory responses. The molecular basis of thermosensation lies in the activation of various thermosensitive ion channels with distinct temperature thresholds expressed on the cell membrane of sensory neurons. These channels are able to convert thermal stimuli into electrical activities by gating ions into and out of the cell. In this chapter, we briefly introduce the physiological functions of the main thermosensitive ion channels involved in the core body temperature homeostasis orchestrated by the neural circuits in the peripheral and central nerve systems.
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