ArticleMolecular and cellular biochemistry2022
Consumption of combined fructose and sucrose diet exacerbates oxidative stress, hypertrophy and CaMKII
Article in Molecular and cellular biochemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 12 citations in OpenAlex.
- Oxidative Modifications in Cardiac Mitochondrial and CaHandbook of experimental pharmacology · 2026Review
- Innovative insights into the effects of a high-sucrose diet on pancreatic health and the therapeutic role of empagliflozin in type 2 diabetes: An experimental study.Animal models and experimental medicine · 2025Article
- Whole tomato lipidic extract improved sperm quality in obese rats induced by a high-carbohydrate diet.Andrology · 2025Article
- Combined fructose and sucrose consumption from an early age aggravates cardiac oxidative damage and causes a dilated cardiomyopathy in SHR rats.Journal of clinical biochemistry and nutrition · 2023Article
- Anti-inflammatory potential of delta-9-tetrahydrocannabinol in hyperinsulinemia: an experimental study.Molecular biology reports · 2022Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
The prevalence of the metabolic syndrome (MetS) and its cardiac comorbidities as cardiac hypertrophy (CH) have increased considerably due to the high consumption of carbohydrates, such as sucrose and/or fructose. We compared the effects of sucrose (S), fructose (F) and their combination (S + F) on the development of MetS in weaned male Wistar rats and established the relationship between the consumption of these sugars and the degree of cardiac CH development, oxidative stress (OS) and Calcium/calmodulin-dependent protein kinase type II subunit delta oxidation (ox-CaMKII
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Registered trials
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