Evidence map›Paper›PMID 35138485›Full record

SynthesisNeurosurgical review2022

Complications associated with subaxial placement of pedicle screws versus lateral mass screws in the cervical spine: systematic review and meta-analysis comprising 1768 patients and 8636 screws.

Mohamed A R Soliman, Slah Khan, Nicco Ruggiero, Brandon L Mariotti, Alexander O Aguirre, Cathleen C Kuo, Alexander G Fritz, Siddharth Sharma, Anxhela Nezha, Bennett R Levy and 8 more

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Neurosurgical review, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
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  5. Review
  6. Revealing the potential: radiological assessment of pedicle screw placement in the craniocervical junction and upper cervical spine.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 2 countries.

Mohamed A R SolimanDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, 100 High Street, Suite B4, Buffalo, NY, 14203, USA.ORCID http://orcid.org/0000-0003-1855-2551
Slah KhanJacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
Nicco RuggieroJacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
Brandon L MariottiJacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
Alexander O AguirreJacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.ORCID http://orcid.org/0000-0002-3971-8963
Cathleen C KuoJacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
Alexander G FritzJacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
Siddharth SharmaJacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
Anxhela NezhaJacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
Bennett R LevySchool of Medicine and Health Sciences, George Washington University, Washington, DC, USA.
Asham KhanDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, 100 High Street, Suite B4, Buffalo, NY, 14203, USA.ORCID http://orcid.org/0000-0003-2593-8831
Amany A SalemDepartment of Public Health and Community Medicine, Faculty of Medicine, Cairo University, Cairo, Egypt.
Patrick K JowdyDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, 100 High Street, Suite B4, Buffalo, NY, 14203, USA.
Qazi ZeeshanDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, 100 High Street, Suite B4, Buffalo, NY, 14203, USA.
Moleca M GhannamDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, 100 High Street, Suite B4, Buffalo, NY, 14203, USA.
Robert V StarlingDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, 100 High Street, Suite B4, Buffalo, NY, 14203, USA.
John PollinaDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, 100 High Street, Suite B4, Buffalo, NY, 14203, USA.ORCID http://orcid.org/0000-0002-6234-4517
Jeffrey P MullinDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, 100 High Street, Suite B4, Buffalo, NY, 14203, USA. Jmullin@ubns.com.ORCID http://orcid.org/0000-0003-0640-2329
Jacobs (United States) · USKaleida Health · USCairo University · EGGeorge Washington University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lateral mass screw (LMS) fixation for the treatment of subaxial cervical spine instability or deformity has been traditionally associated with few neurovascular complications. However, cervical pedicle screw (CPS) fixation has recently increased in popularity, especially with navigation assistance, because of the higher pullout strength of the pedicle screws. To their knowledge, the authors conducted the first meta-analysis comparing the complication rates during and/or after CPS and LMS placement for different pathologies causing cervical spine instability. A systematic literature search of PubMed and Embase from inception to January 12, 2021 was performed to identify studies reporting CPS and/or LMS-related complications. Complications were categorized into intraoperative and early postoperative (within 30 days of surgery) and late postoperative (after 30 days from surgery) complications. All studies that met the prespecified inclusion criteria were pooled and cumulatively analyzed. A total of 24 studies were conducted during the time frame of the search and comprising 1768 participants and 8636 subaxially placed screws met the inclusion criteria. The CPS group experienced significantly more postoperative C5 palsy (odds ratio [OR] = 3.48, 95% confidence interval [CI] = 1.27-9.53, p < 0.05). Otherwise, there were no significant differences between the LMS and CPS groups. There were no significant differences between the CPS and LMS groups in terms of neurovascular procedure-related complications other than significantly more C5 palsy in the CPS group.

Indexed as

Pedicle ScrewsSpinal DiseasesSpinal FusionCervical VertebraeHumansParalysisTomography, X-Ray ComputedTreatment OutcomeC5 palsyComplicationInstrumentation failureLateral mass screwsPedicle screwsSpinal cord injuryVertebral artery injury

Identifiers

PMID35138485
OpenAlexW4210913326

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.