Evidence map›Paper›PMID 35138443›Full record

ReviewMammalian genome : official journal of the International Mammalian Genome Society2022

The mouse resource at National Resource Center for Mutant Mice.

Cunxiang Ju, Juan Liang, Mingkun Zhang, Jinlong Zhao, Ling'en Li, Shuai Chen, Jing Zhao, Xiang Gao

Open access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Mammalian genome : official journal of the International Mammalian Genome Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. The mouse resource at National Resource Center for Mutant Mice of China.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Review
  2. Article
  3. A Monocytic Barrier to the Humanization of Immunodeficient Mice.Current stem cell research & therapy · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Cunxiang Ju *GemPharmatech Co., Ltd, Nanjing, China.
Juan Liang *GemPharmatech Co., Ltd, Nanjing, China.
Mingkun ZhangGemPharmatech Co., Ltd, Nanjing, China.
Jinlong ZhaoGemPharmatech Co., Ltd, Nanjing, China.
Ling'en LiGemPharmatech Co., Ltd, Nanjing, China.
Shuai ChenModel Animal Research Center of Nanjing University, Nanjing, China.
Jing ZhaoGemPharmatech Co., Ltd, Nanjing, China. zhaojing@gempharmatech.com.
Xiang GaoNational Resource Center for Mutant Mice, Nanjing, China. gaoxiang@nju.edu.cn.ORCID 0000-0002-0436-0324
Taiwan Semiconductor Manufacturing Company (China) · CNModel Animal Research Center · CNNanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mouse models are essential for dissecting disease mechanisms and defining potential drug targets. There are more than 18,500 mouse strains available for research communities in National Resource Center for Mutant Mice (NRCMM) of China, affiliated with Model Animal Research Center of Nanjing University and Gempharmatech Company. In 2019, Gempharmatech launched the Knockout All Project (KOAP) aiming to generate null mutants and gene floxed strains for all protein-coding genes in mouse genome within 5 years. So far, KOAP has generated 8,004 floxed strains and 9,769 KO (knockout) strains (updated to Oct, 2021). NRCMM also created hundreds of Cre transgenic lines, mutant knock-in models, immuno-deficient models, and humanized mouse models. As a member of the international mouse phenotyping consortium (IMPC), NRCMM provides comprehensive phenotyping services for mouse models. In summary, NRCMM will continue to support biomedical community with new mouse models as well as related services.

Indexed as

GenomeAnimalsChinaDisease Models, AnimalHumansMiceMice, KnockoutPhenotypeHumanized miceKnockoutMouse resourceTransgenic mice

Identifiers

PMID35138443
OpenAlexW4210864514

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.