ArticleFEMS microbiology ecology2022
Exposure to lysed bacteria can promote or inhibit growth of neighboring live bacteria depending on local abiotic conditions.
Article in FEMS microbiology ecology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 23 citations in OpenAlex.
- Article
- Article
- Exploring the intersection between necromass reutilization and genome protection reveals novel proteins that contribute to both processes in Ustilago maydis.Biology direct · 2026Article
- Biomolecules Generated During Programmed Cell Death (PCD) Enhance the Capacity of Proliferating Ustilago maydis Cells to Overcome the Negative Impacts of Non-PCD Necromass.Microbial ecology · 2026Article
- Bacterial necromass recycling promotes diversity maintenance in bacterial communities via resource partitioning.Nature ecology & evolution · 2026Article
- Unveiling the antibacterial effects of endolysin POE and holin Hol8 from Pseudomonas otitidis phage vB_PotS-PotUPM1.World journal of microbiology & biotechnology · 2026Article
- Skin-associatedmSphere · 2025Article
- Persistent enrichment of multidrug-resistant Klebsiella in oral and nasal communities during long-term starvation.Microbiome · 2024Article
- Balance between asymmetric allocation and repair of somatic damage in unicellular life forms as an ancient form of r/K selection.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Skin-associatedbioRxiv : the preprint server for biology · 2024Article
- Influence of Dead Cells Killed by Industrial Biocides (BAC and DBNPA) on Biofilm Formation.Antibiotics (Basel, Switzerland) · 2024Article
- Unicellular life balances asymmetric allocation and repair of somatic damage representing the origin of r/K selection.bioRxiv : the preprint server for biology · 2023Article
- Effect of respiratory tract co-colonizers on initial attachment of Neisseria meningitidis.Archives of microbiology · 2023Article
- Mode of killing determines the necrotrophic response of oral bacteria.Journal of oral microbiology · 2023Article
- Natural detoxification of antibiotics in the environment: A one health perspective.Frontiers in microbiology · 2022Review
- Antibiotic Breakdown by Susceptible Bacteria Enhances the Establishment of β-Lactam Resistant Mutants.Frontiers in microbiology · 2021Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microbial death is extremely common in nature, yet the ecological role of dead bacteria is unclear. Dead cells are assumed to provide nutrients to surrounding microbes, but may also affect them in other ways. We found that adding lysate prepared from dead bacteria to cultures of Escherichia coli in nutrient-rich conditions suppressed their final population density. This is in stark contrast with the notion that the primary role of dead cells is nutritional, although we also observed this type of effect when we added dead bacteria to cultures that were not supplied with other nutrients. We only observed the growth-suppressive effect of our dead-bacteria treatment after they had undergone significant lysis, suggesting a key role for cellular contents released during lysis. Transcriptomic analysis indicated changes in gene expression in response to dead cells in growing populations, particularly in genes involved in motility. This was supported by experiments with genetic knockouts and copy-number manipulation. Because lysis is commonplace in natural and clinical settings, the growth-suppressive effect of dead cells we describe here may be a widespread and previously unrecognized constraint on bacterial population growth.
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