SynthesisEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2022
Long-term clinical impact of permanent pacemaker implantation in patients undergoing transcatheter aortic valve implantation: a systematic review and meta-analysis.
Synthesis in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- Long-term outcome of patients undergoing pacemaker implantation after transcatheter aortic valve implantation: a systematic review and meta-analysis.Cardiovascular intervention and therapeutics · 2026Pooled it
- Association of the HIGS score with permanent pacemaker implantation and mortality after transcatheter aortic valve implantation.Annals of medicine · 2026Article
- Balloon-Expandable Versus Self-Expandable Transcatheter Aortic Valve Implantation Devices: A Contemporary Systematic Review.Journal of clinical medicine · 2026Review
- Inflammation After Transcatheter Aortic Valve Implantation: Mechanisms, Risk Stratification, and Therapeutic Implications.Reviews in cardiovascular medicine · 2026Review
- Impact of Early Nonfatal Complications After Transcatheter Aortic Valve Implantation on 1-Year Mortality and Quality of Life: Insights From the LANDMARK Trial.Structural heart : the journal of the Heart Team · 2026Article
- Prognostic Impact of Gait Speed Changes During Hospitalization in Patients Undergoing Transcatheter Aortic Valve Implantation.Circulation reports · 2026Article
- Optimized Balloon-Expandable Transcatheter Aortic Valve Implantation and Clinical Outcomes.JACC. Advances · 2026Article
- Prognostic Impact of Pacemaker Implantation in Transcatheter Aortic Valve Replacement With Self-Expanding Prosthesis.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026Observational
- Ct-derived basal septal thickness predicts Post-TAVR pacemaker implantation in patients with preexisting right bundle branch block.International journal of cardiology. Heart & vasculature · 2026Article
- Permanent Pacemaker Implantation Following Transcatheter Aortic Valve Replacement: Incidence, Predictors, and Association With Reduced Ischemic Stroke Risk.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026Article
- Evaluation of the Effectiveness of a Novel Wireless Energy-Transmitting Implantable Diaphragm Pacemaker in Anesthetized Pigs.Bioengineering (Basel, Switzerland) · 2026Article
- Conduction Abnormalities After Transcatheter Aortic Valve Replacement: Comprehensive Review of Current Literature, Guidelines, and Clinical Practices.Reviews in cardiovascular medicine · 2026Review
- Permanent Pacemaker Implantation After TAVI and Its Association with Survival: Single-Center Cohort and Nationwide Validation.Journal of clinical medicine · 2026Article
- Conduction disorders after combined surgical or transcatheter treatment for severe aortic stenosis and coronary artery disease.BMC cardiovascular disorders · 2026Article
- Article
- Preprocedural CT and ECG Markers for Predicting Post-TAVR Pacemaker Requirement in High-Risk Patients.Structural heart : the journal of the Heart Team · 2025Article
- Prospective Observational Study on the Accuracy of Predictors of Permanent Pacemaker Secondary to High-Grade Atrioventricular Conduction Block After TAVI (CONDUCT-TAVI).Circulation. Cardiovascular interventions · 2025Observational
- Impact of Basal Septal Bulge on Conduction Disturbance After Transcatheter Aortic Valve Replacement Using ACURATE neo/neo2.Structural heart : the journal of the Heart Team · 2025Article
- Prognostic Role of Ventricular Pacing Burden in Patients with Pacemaker Implantation After TAVR.Medicina (Kaunas, Lithuania) · 2025Article
- Rapid Atrial Pacing After TAVI for Pacemaker Prediction.Reviews in cardiovascular medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThe aims of this study is to assess by an updated meta-analysis the clinical outcomes related to permanent pacemaker implantation (PPI) after transcatheter aortic valve implantation (TAVI) at long-term (≥12 months) follow-up (LTF). METHODS AND
resultsA comprehensive literature research was performed on PubMed and EMBASE. The primary endpoint was all-cause death. Secondary endpoints were rehospitalization for heart failure, stroke, and myocardial infarction. A subgroup analysis was performed according to the Society of Thoracic Surgeon-Predicted Risk of Mortality (STS-PROM) score. This study is registered with PROSPERO (CRD42021243301). A total of 51 069 patients undergoing TAVI from 31 observational studies were included. The mean duration of follow-up was 22 months. At LTF, PPI post-TAVI was associated with a higher risk of all-cause death [risk ratio (RR) 1.18, 95% confidence interval (CI) 1.10-1.25; P < 0.001] and rehospitalization for heart failure (RR 1.32, 95% CI 1.13-1.52; P < 0.001). In contrast, the risks of stroke and myocardial infarction were not affected. Among the 20 studies that reported procedural risk, the association between PPI and all-cause death risk at LTF was statistically significant only in studies enrolling patients with high STS-PROM score (RR 1.25, 95% CI 1.12-1.40), although there was a similar tendency of the results in those at medium and low risk.
conclusionPatients necessitating PPI after TAVI have a higher long-term risk of all-cause death and rehospitalization for heart failure as compared to those who do not receive PPI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.