Evidence map›Paper›PMID 35138170›Full record

ArticleMicrobiology spectrum2022

Inactivation of the Response Regulator AgrA Has a Pleiotropic Effect on Biofilm Formation, Pathogenesis and Stress Response in Staphylococcus lugdunensis.

Marion Aubourg, Marine Pottier, Albertine Léon, Benoit Bernay, Anne Dhalluin, Margherita Cacaci, Riccardo Torelli, Pierre Ledormand, Cecilia Martini, Maurizio Sanguinetti and 3 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. First whole genome sequencing ofOpen veterinary journal · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Lugdunin production and activity inMicrobiology spectrum · 2023
    Article
  9. Article
  10. Article
  11. Tannin extracted fromFrontiers in microbiology · 2023
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Marion AubourgUniversité de Caen Normandie, Dynamicure, INSERM U1311, CHU de Caen, Caen, France.
Marine PottierUniversité de Caen Normandie, Dynamicure, INSERM U1311, CHU de Caen, Caen, France.
Albertine LéonUniversité de Caen Normandie, Dynamicure, INSERM U1311, CHU de Caen, Caen, France.
Benoit BernayPlateforme Proteogen SFR ICORE 4206, Université de Caen Normandie, Caen, France.
Anne DhalluinUniversité de Caen Normandie, Dynamicure, INSERM U1311, CHU de Caen, Caen, France.
Margherita CacaciInstitute of Microbiology, Catholic University of Sacred Heart, L. go F. Vito 1, Rome, Italy.
Riccardo TorelliInstitute of Microbiology, Catholic University of Sacred Heart, L. go F. Vito 1, Rome, Italy.
Pierre LedormandUniversité de Caen Normandie, ABTE, Caen, France.
Cecilia MartiniInstitute of Microbiology, Catholic University of Sacred Heart, L. go F. Vito 1, Rome, Italy.
Maurizio SanguinettiInstitute of Microbiology, Catholic University of Sacred Heart, L. go F. Vito 1, Rome, Italy.
Michel AuzouCHU de Caen, Laboratoire de Microbiologie, Caen, France.
François GraveyUniversité de Caen Normandie, Dynamicure, INSERM U1311, CHU de Caen, Caen, France.ORCID 0000-0001-8672-8286
Jean-Christophe GiardUniversité de Caen Normandie, Dynamicure, INSERM U1311, CHU de Caen, Caen, France.ORCID 0000-0001-8588-2732
Inserm · FRUniversità Cattolica del Sacro Cuore · ITAliments Bioprocédés Toxicologie EnvironnementsCentre Hospitalier Universitaire de Caen Normandie · FRUniversité de Caen Normandie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Staphylococcus lugdunensis is a coagulase-negative Staphylococcus that emerges as an important opportunistic pathogen. However, little is known about the regulation underlying the transition from commensal to virulent state. Based on knowledge of S. aureus virulence, we suspected that the

Indexed as

BiofilmsAnimalsBacterial ProteinsGene Expression Regulation, BacterialHumansHydrogen PeroxideMaleMiceMice, Inbred BALB CStaphylococcal InfectionsStaphylococcus lugdunensisVirulenceBacterial ProteinsHydrogen PeroxideAgrAagr systemStaphylococcus lugdunensistranscriptional regulation

Identifiers

PMID35138170
PMCPMC8826819
OpenAlexW4210862957

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.