ArticleEinstein (Sao Paulo, Brazil)2022
COVID-19 related acute genital ulcer: a case report.
Article in Einstein (Sao Paulo, Brazil), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- COVID-19, Coronavirus Vaccines, and Possible Association with Lipschütz Vulvar Ulcer: A Systematic Review.Clinical reviews in allergy & immunology · 2023Pooled it
- COVID 19 vaccination as a trigger of acute genital ulcers in an immunocompromised adolescent-case study and literature review.BMC women's health · 2024Review
- Acute Genital Ulcers in a Woman Secondary to COVID-19 Infection: A Case Report.Clinical, cosmetic and investigational dermatology · 2024Article
- Lipschütz Ulcer and SARS-CoV-2: What We Currently Know?Diseases (Basel, Switzerland) · 2023Review
- Female genital mucosal lesions associated with COVID-19 vaccination: A brief review of the literature.Journal of the European Academy of Dermatology and Venereology : JEADV · 2023Review
- Acute vulvar ulcers and the COVID-19 booster vaccine.JAAD case reports · 2022Article
- Genital Ulcer as a Complication of COVID-19 Infection: A Case Report.American journal of men's healthArticle
Corrections and comments
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Authors and funding
6 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute vulvar ulcer (Lipschütz's ulcer) is a rare lesion with local hyperimmunoreactivity triggered by infection, which is characterized by acute, painful, and necrotic ulcerations. This condition is usually found in non-sexually active adolescents, and it resolves spontaneously. We report a case of a 35-year-old woman who was diagnosed with COVID-19 who did not have severe symptoms, but had high levels of D-dimer for 9 days. The COVID-19 diagnosis was followed by the appearance of an acute, necrotic, extremely painful vulvar ulcer, although symptoms caused by COVID-19 had improved. We emphasize the importance of the differential diagnosis to exclude diseases such as Behçet's syndrome, Sexually Transmitted Infections, as well as the presence of viruses that generally trigger Lipschütz's ulcer, such as Epstein-Barr virus and cytomegalovirus. No treatment is usually necessary, however, in the present report due to the pain experienced by the patient, we successfully used oral prednisone.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.