Evidence map›Paper›PMID 35137778›Full record

ArticleArquivos brasileiros de cardiologia2022

Cost-Effectiveness Analysis of CCTA in SUS, as Compared to Other Non-Invasive Imaging Modalities in Suspected Obstructive CAD.

Patricia Bastos do Carmo, Carlos Alberto da Silva Magliano, Helena Cramer Veiga Rey, Gabriel C Camargo, Luís Filipe Lannes Trocado, Ilan Gottlieb

Open access · diamondAbstract read
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Guideline
  2. Guideline
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Patricia Bastos do CarmoInstituto Nacional de Cardiologia , Rio de Janeiro , RJ - Brasil.ORCID 0000-0003-0356-0540
Carlos Alberto da Silva MaglianoInstituto Nacional de Cardiologia , Rio de Janeiro , RJ - Brasil.ORCID 0000-0003-0210-4877
Helena Cramer Veiga ReyInstituto Nacional de Cardiologia , Rio de Janeiro , RJ - Brasil.ORCID 0000-0003-3920-5815
Gabriel C CamargoInstituto Nacional de Cardiologia , Rio de Janeiro , RJ - Brasil.ORCID 0000-0001-5203-6097
Luís Filipe Lannes TrocadoInstituto Nacional de Cardiologia , Rio de Janeiro , RJ - Brasil.
Ilan GottliebInstituto Nacional de Cardiologia , Rio de Janeiro , RJ - Brasil.ORCID 0000-0003-0402-5769
Dean College · USInstituto Nacional de Cardiologia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Brazilian public health system does not include computed tomography angiography (CTA).

objectiveRank, according to the Brazilian public health system, the cost-effectiveness of different strategies for the diagnosis of coronary artery disease (CAD), combining exercise tests (ET), myocardial scintigraphy (MS), stress echocardiography (SE), and CTA in a hypothetical intermediate pre-test probability cohort of patients.

methodsThis study implemented a cost-effectiveness analysis through a decision tree. The incremental cost-effectiveness ratio (ICER) and net benefit were analyzed by adopting multiple thresholds of willingness to pay, from 0.05 to 1 GDP per capita per correct diagnosis. In sequential tests, a second confirmatory test was performed only when the first was positive.

resultsAfter excluding dominated or extended dominance diagnostic strategies, the efficiency frontier consisted of three strategies: ET, ET followed by SE, and SE followed by CTA, the last being the most cost-effective strategy. Through the net benefit, the ranking of the most cost-effective strategies varied according to willingness to pay.

conclusionsUsing current concepts of health technology assessment, this study provides a ranking for decision-making concerning which diagnostic strategy to use in a population with an intermediate pre-test risk for CAD. With a feasible cost estimate adopted for CTA, the impact of including this to the list of the diagnostic arsenal would represent a cost-effective strategy in most of the evaluated scenarios with broad variations in the willingness to pay.

Indexed as

Coronary Artery DiseaseMyocardial Perfusion ImagingComputed Tomography AngiographyCoronary AngiographyCost-Benefit AnalysisEchocardiography, StressHumans

Identifiers

PMID35137778
PMCPMC8959029
OpenAlexW4200517144

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.