Evidence map›Paper›PMID 35137571›Full record

ArticleCancer medicine2022

Clinical significance of CD8-positive lymphocytes on tumor cell clusters of ascites cell block in ovarian high-grade serous carcinoma.

Hideki Iwahashi, Morikazu Miyamoto, Tsubasa Ito, Jin Suminokura, Taira Hada, Hiroki Ishibashi, Soichiro Kakimoto, Hiroko Matsuura, Rie Suzuki, Shinya Minabe and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Hideki IwahashiDepartment of Obstetrics and Gynecology, National Defense Medical College Hospital, Tokorozawa, Japan.
Morikazu MiyamotoDepartment of Obstetrics and Gynecology, National Defense Medical College Hospital, Tokorozawa, Japan.ORCID 0000-0003-4763-0926
Tsubasa ItoDepartment of Obstetrics and Gynecology, National Defense Medical College Hospital, Tokorozawa, Japan.
Jin SuminokuraDepartment of Obstetrics and Gynecology, National Defense Medical College Hospital, Tokorozawa, Japan.
Taira HadaDepartment of Obstetrics and Gynecology, National Defense Medical College Hospital, Tokorozawa, Japan.
Hiroki IshibashiDepartment of Obstetrics and Gynecology, National Defense Medical College Hospital, Tokorozawa, Japan.
Soichiro KakimotoDepartment of Obstetrics and Gynecology, National Defense Medical College Hospital, Tokorozawa, Japan.
Hiroko MatsuuraDepartment of Obstetrics and Gynecology, National Defense Medical College Hospital, Tokorozawa, Japan.
Rie SuzukiDepartment of Obstetrics and Gynecology, National Defense Medical College Hospital, Tokorozawa, Japan.
Shinya MinabeDepartment of Laboratory Medicine, National Defense Medical College Hospital, Tokorozawa, Japan.
Susumu MatsukumaDepartment of Laboratory Medicine, National Defense Medical College Hospital, Tokorozawa, Japan.
Hitoshi TsudaDepartment of Basic Pathology, National Defense Medical College Hospital, Tokorozawa, Japan.
Masashi TakanoDepartment of Obstetrics and Gynecology, National Defense Medical College Hospital, Tokorozawa, Japan.
National Defense Medical College Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe clinical significance of CD8-positive (CD8

methodsAmong HGSC patients who underwent surgery from January 2014 to December 2019, 38 patients with ascites cell block were selected. Using these cell blocks and primary ovarian tumor tissue, the presence of CD8

resultsIn total, 38 cases were identified: 25 (65.8%) in Group A and 13 (34.2%) in Group B. More cases in Group A were positive for CD4 (p < 0.01), PD-L1 (p = 0.02), FoxP3 (p = 0.02) and had a higher number of CD8

conclusionThe presence of CD8

Indexed as

CarcinomaOvarian NeoplasmsAscitesB7-H1 AntigenCD8-Positive T-LymphocytesFemaleHumansLymphocytes, Tumor-InfiltratingPrognosisRetrospective StudiesB7-H1 Antigenascites cell blockCD8-positive lymphocyteshigh-grade serous carcinomahybrid cell countimmunohistochemical staining

Identifiers

PMID35137571
PMCPMC9119359
OpenAlexW4211092865

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.