Evidence map›Paper›PMID 35137235›Full record

ArticleSchizophrenia bulletin2022

Childhood Maltreatment, Educational Attainment, and IQ: Findings From a Multicentric Case-control Study of First-episode Psychosis (EU-GEI).

Lucia Sideli, Adriano Schimmenti, Daniele La Barbera, Caterina La Cascia, Laura Ferraro, Monica Aas, Luis Alameda, Eva Velthorst, Helen L Fisher, Vincenzo Caretti and 34 more

Open access · greenAbstract read
In one paragraph

Article in Schizophrenia bulletin, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

44 authors at 20 institutions in 8 countries.

Lucia SideliDepartment of Human Science, LUMSA University, Rome, Italy.ORCID 0000-0001-6124-6897
Adriano SchimmentiFaculty of Human and Social Sciences, UKE - Kore University of Enna, Enna, Italy.
Daniele La BarberaDepartment of Biomedicine, Neuroscience, and Advanced Diagnostic, University of Palermo, Palermo, Italy.
Caterina La CasciaDepartment of Biomedicine, Neuroscience, and Advanced Diagnostic, University of Palermo, Palermo, Italy.
Laura FerraroDepartment of Biomedicine, Neuroscience, and Advanced Diagnostic, University of Palermo, Palermo, Italy.
Monica AasDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, England.
Luis AlamedaDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, England.
Eva VelthorstDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, USA.
Helen L FisherKing's College London, Social, Genetic, & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, England.
Vincenzo CarettiDepartment of Human Science, LUMSA University, Rome, Italy.
Giulia TrottaDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, England.
Giada TripoliDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, England.
Diego QuattroneKing's College London, Social, Genetic, & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, England.
Charlotte Gayer-AndersonKing's College London, Social, Genetic, & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, England.ORCID 0000-0003-1636-889X
Fabio SeminerioDepartment of Biomedicine, Neuroscience, and Advanced Diagnostic, University of Palermo, Palermo, Italy.
Crocettarachele SartorioDepartment of Biomedicine, Neuroscience, and Advanced Diagnostic, University of Palermo, Palermo, Italy.
Giovanna MarrazzoDepartment of Biomedicine, Neuroscience, and Advanced Diagnostic, University of Palermo, Palermo, Italy.
Antonio LasalviaSection of Psychiatry, Department of Neuroscience, Biomedicine and Movement, University of Verona, Verona, Italy.ORCID 0000-0001-9963-6081
Sarah TosatoSection of Psychiatry, Department of Neuroscience, Biomedicine and Movement, University of Verona, Verona, Italy.
Ilaria TarriconeDepartment of Medical and Surgical Sciences, Alma Mater Studiorum - Bologna University, Italy.
Domenico BerardiDepartment of Biomedical and NeuroMotor Sciences, Psychiatry Unit, Alma Mater Studiorum Università di Bologna, Bologna, Italy.
Giuseppe D'AndreaDepartment of Biomedical and NeuroMotor Sciences, Psychiatry Unit, Alma Mater Studiorum Università di Bologna, Bologna, Italy.
Celso ArangoDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, School of Medicine, Universidad Complutense, ISGM, CIBERSAM, Madrid, Spain.
Manuel ArrojoDepartment of Psychiatry, Psychiatric Genetic Group, Instituto de Investigación Sanitaria de Santiago de Compostela, Complejo Hospitalario Universitario de  Santiago de Compostela, Santiago, Spain.
Miguel BernardoBarcelona Clinic Schizophrenia Unit, Hospital Clinic, Department of Medicine, Neuroscience Institute, University of Barcelona, Institut d'Investigacions Biomèdiques, August Pi I Sunyer, Centro de Investigación Biomédica en Red de Salud Mental, Barcelona, Spain.
Julio BobesDepartment of Medicine, Psychiatry Area, Universidad de Oviedo, ISPA, INEUROPA, CIBERSAM, Oviedo, Spain.
Julio SanjuánDepartment of Psychiatry, Centro de Investigación Biomédica en Red de Salud Mental, School of Medicine, Universidad de Valencia, Valencia, Spain.
Jose Luis SantosDepartment of Psychiatry, Hospital "Virgen de la Luz", Cuenca, Spain.
Paulo Rossi MenezesDepartment of Preventive Medicine, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Cristina Marta Del-BenDivision of Psychiatry, Department of Neuroscience and Behaviour, Ribeirão Preto Medical School, Universidade de São Paulo, São Paulo, Brazil.
Hannah E JongsmaPsyLife Group, Division of Psychiatry, University College London, London, England.
Peter B JonesCAMEO Early Intervention Service, Cambridgeshire and Peterborough National Health Service Foundation Trust, Cambridge, England.
James B KirkbridePsyLife Group, Division of Psychiatry, University College London, London, England.ORCID 0000-0003-3401-0824
Pierre-Michel LlorcaEA 7280 Npsydo, Université Clermont Auvergne, Clermont-Ferrand, France.
Andrea TortelliEstablissement Public de Santé, Maison Blanche, Paris, France.
Baptiste PignonAP-HP, Groupe Hospitalier "Mondor," Pôle de Psychiatrie, Créteil, France.ORCID 0000-0003-0526-3136
Lieuwe de HaanEarly Psychosis Section, Department of Psychiatry, Amsterdam UMC, Amsterdam, The Netherlands.
Jean-Paul SeltenInstitute for Mental Health, GGZ Rivierduinen, Leiden, The Netherlands.
Jim Van OsDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, England.
Bart P RuttenDepartment of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands.
Marta Di FortiKing's College London, Social, Genetic, & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, England.
Craig MorganESRC Centre for Society and Mental Health, King's College London, London, UK.
Robin M MurrayDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, England.
EU-GEI WP2 Group
King's College London · GBUniversity of Palermo · ITInserm · FRUniversity of Bologna · ITComplejo Hospitalario Universitario de Santiago · ESLibera Università Maria SS. Assunta · ITMaastricht University Medical Centre · NLUniversidade de São Paulo · BRUniversitat de València · ESUniversity of Verona · ITAmsterdam Neuroscience · NLCentro de Investigación Biomédica en Red de Salud Mental · ESHospital General Universitario Gregorio Marañón · ESHospital Virgen de la Luz · ESNational Health Service · GBOslo University Hospital · NOUniversidad de Oviedo · ESUniversità degli Studi di Enna Kore · ITUniversité Clermont Auvergne · FRUniversity College London · GB

Funding

Department of Health
6 · The paper itself

Abstract

background and hypothesisEvidence suggests that childhood maltreatment (ie, childhood abuse and childhood neglect) affects educational attainment and cognition. However, the association between childhood maltreatment and Intelligence Quotient (IQ) seems stronger among controls compared to people with psychosis. We hypothesised that: the association between childhood maltreatment and poor cognition would be stronger among community controls than among people with first-episode of psychosis (FEP); compared to abuse, neglect would show stronger associations with educational attainment and cognition; the association between childhood maltreatment and IQ would be partially accounted for by other risk factors; and the association between childhood maltreatment, educational attainment, and IQ would be stronger among patients with affective psychoses compared to those with nonaffective psychoses. STUDY

design829 patients with FEP and 1283 community controls from 16 EU-GEI sites were assessed for child maltreatment, education attainment, and IQ. STUDY

resultsIn both the FEP and control group, childhood maltreatment was associated with lower educational attainment. The association between childhood maltreatment and lower IQ was robust to adjustment for confounders only among controls. Whereas childhood neglect was consistently associated with lower attainment and IQ in both groups, childhood abuse was associated with IQ only in controls. Among both patients with affective and nonaffective psychoses, negative associations between childhood maltreatment and educational attainment were observed, but the crude association with IQ was only evident in affective psychoses.

conclusionsOur findings underscore the role of childhood maltreatment in shaping academic outcomes and cognition of people with FEP as well as controls.

Indexed as

Child AbusePsychotic DisordersAffective Disorders, PsychoticCase-Control StudiesChildHumansIntelligence Testschildhood abusechildhood neglectIQpsychosisschizophrenia

Identifiers

PMID35137235
PMCPMC9077421
OpenAlexW4205133084

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.