Evidence map›Paper›PMID 35136206›Full record

ArticleNature reviews. Endocrinology2022

An integrated model of obesity pathogenesis that revisits causal direction.

David S Ludwig, Thorkild I A Sørensen

Abstract read
PubMed Publisher
In one paragraph

Article in Nature reviews. Endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Carbohydrate-insulin model: does the conventional view of obesity reverse cause and effect?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  8. Implication of lipid turnover for the control of energy balance.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
  9. An adiposity force induces obesity in humans independently of a normal energy balance system-a thought experiment.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  10. Energy homeostasis from Lavoisier to control theory.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  11. Article
  12. Article
  13. Observational
  14. Article
  15. The social origins of obesity within and across generations.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023
    Review
  16. An American Physiological Society cross-journal Call for Papers on "The Physiology of Obesity".American journal of physiology. Lung cellular and molecular physiology · 2022
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

David S LudwigNew Balance Foundation Obesity Prevention Center, Boston Children's Hospital, Boston, MA, USA. david.ludwig@childrens.harvard.edu.ORCID http://orcid.org/0000-0003-3307-8544
Thorkild I A SørensenDepartment of Public Health and Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. tias@sund.ku.dk.ORCID http://orcid.org/0000-0003-4821-430X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ObesityHumansRetrospective StudiesTime Factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.