ArticlePediatric research2022
Pediatric central venous access devices: practice, performance, and costs.
Article in Pediatric research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Paediatric Central Venous Access Devices: An Evidence and Gap Map of Global Research.Journal of paediatrics and child health · 2026Pooled it
- Clinical Trials in Central Venous Access Devices: An Evidence and Gap Map.Journal of advanced nursing · 2026Pooled it
- Risk factors and incidence of central venous access device-related thrombosis in hospitalized children: a systematic review and meta-analysis.Pediatric research · 2024Pooled it
- Peripherally inserted central catheter design and material for reducing catheter failure and complications.The Cochrane database of systematic reviews · 2024Pooled it
- Central venous access device-associated complication costs in paediatric cancer care.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Observational
- Missing data, missed risks: complications and documentation gaps of central venous access devices in pediatric oncology.BMC pediatrics · 2026Article
- Umbilical venous catheter and peripherally inserted central catheter malposition and tip migration in neonates: A mixed methods cost analysis.International journal of nursing studies advances · 2025Article
- A Prospective Cohort Study of Technique and Technology Used to Improve First Time PIVC Insertion Success in Hospitalised Paediatric Patients.Journal of advanced nursing · 2025Observational
- Strategies for Assessing Physical Compatibility of Calcium Folinate with Bicarbonate During Methotrexate Rescue Therapy in Pediatric Patients with Acute Lymphoblastic Leukemia.Pharmaceutics · 2025Article
- Incidence and risk factors of complications during central venous access devices removal in children.The journal of vascular access · 2025Article
- Development and validation of a nomogram risk prediction model for PICC-related thrombosis in children with hematological malignancies.Clinical and experimental medicine · 2025Article
- Pediatric invasive device utility and harm: a multi-site point prevalence survey.Pediatric research · 2024Observational
- Inappropriate Use of Peripherally Inserted Central Catheters in Pediatrics: A Multisite Study.Hospital pediatrics · 2024Article
- Michigan appropriateness guide for intravenous catheters in pediatrics - miniMAGIC-Brasil: translation into Brazilian portuguese.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2024Article
- Vascular access devices and associated complications in paediatric critical care: A prospective cohort study.PloS one · 2024Observational
- The impact of central line bundles on the timing of catheter-associated bloodstream infections and their microbiological distribution in critically ill children.European journal of pediatrics · 2023Article
- Experiences of children with central venous access devices: a mixed-methods study.Pediatric research · 2023Article
- The experiences of adolescents living with a central venous access device: A qualitative analysis.International journal of nursing studies advances · 2022Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHealthcare delivery is reliant on a functional central venous access device (CVAD), but the knowledge surrounding the burden of pediatric CVAD-associated harm is limited.
methodsA prospective cohort study at a tertiary-referral pediatric hospital in Australia. Children <18 years undergoing insertion of a CVAD were screened from the operating theatre and intensive care unit records, then assessed bi-weekly for up to 3 months. Outcomes were CVAD failure and complications, and associated healthcare costs (cost of complications).
results163 patients with 200 CVADs were recruited and followed for 6993 catheter days, with peripherally inserted central catheters most common (n = 119; 60%). CVAD failure occurred in 20% of devices (n = 30; 95% CI: 15-26), at an incidence rate (IR) of 5.72 per 1000 catheter days (95% CI: 4.09-7.78). CVAD complications were evident in 43% of all CVADs (n = 86; 95% CI: 36-50), at a rate of 12.29 per 1000 catheter days (95% CI: 9.84-15.16). CVAD failure costs were A$826 per episode, and A$165,372 per 1000 CVADs. Comparisons between current and recommended practice revealed inconsistent use of ultrasound guidance for insertion, sub-optimal tip-positioning, and appropriate device selection.
conclusionsCVAD complications and failures represent substantial burdens to children and healthcare. Future efforts need to focus on the inconsistent use of best practices. IMPACT: Current surveillance of central venous access device (CVAD) performance is likely under-estimating actual burden on pediatric patients and the healthcare system. CVAD failure due to complication was evident in 20% of CVADs. Costs associated with CVAD complications average at $2327 (AUD, 2020) per episode. Further investment in key diverse practice areas, including new CVAD types, CVAD pathology-based occlusion and dislodgment strategies, the appropriate use of device types, and tip-positioning technologies, will likely lead to extensive benefit.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.