ReviewPediatric research2023
High-frequency ventilation in preterm infants and neonates.
Review in Pediatric research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- High-frequency oscillatory ventilation versus conventional ventilation for infants with severe pulmonary dysfunction born at or near term.The Cochrane database of systematic reviews · 2025Pooled it
- Higher PEEP reduces duration of mechanical ventilation in neonatal respiratory distress syndrome of late preterm and term newborn infants.Scientific reports · 2025Trial
- Lung recruitment with HFOV versus VTV/AC in preterm infants with RDS.BMC pediatrics · 2024Trial
- Temporal Dynamics and Clinical Relevance of Oscillatory Amplitude Variability During High-Frequency Oscillatory Ventilation With Volume Guarantee in Preterm Infants.Pediatric pulmonology · 2026Article
- High-frequency oscillatory ventilation during physiological-based cord clamping attenuates inflammation in preterm lambs.Archives of disease in childhood. Fetal and neonatal edition · 2026Article
- Non-invasive respiratory support attenuates lung damage in a murine model of bronchopulmonary dysplasia.Frontiers in pediatrics · 2026Article
- Multimodal Implementations to Reduce Neonatal Ventilator-Associated Pneumonia and Colistin Use: An Interrupted Time Series.Antibiotics (Basel, Switzerland) · 2025Article
- Preterm infants on high-frequency oscillatory ventilation: electrical impedance tomography during lung recruitment.Pediatric research · 2025Observational
- Risk factors for mortality in neonatal ARDS: a multicenter retrospective cohort study in China.Frontiers of medicine · 2025Article
- High-frequency oscillatory ventilation with sigh breath increases pneumothorax in neonates born at 22-25 gestational weeks.BMC pediatrics · 2025Article
- Article
- Invasive Ventilation Strategies in Neonates.Indian pediatrics · 2025Review
- Intermittent sigh breaths during high-frequency oscillatory ventilation among newborn infants.Clinical and experimental pediatrics · 2025Article
- Assessing Semiregional Cerebral Oxygen Consumption (CMRONMR in biomedicine · 2025Article
- miR-221-3p, arterial blood gas, and lung ultrasound: a multimodal approach for predicting neonatal respiratory distress syndrome outcomes.Journal of cardiothoracic surgery · 2025Article
- Neonatal pulmonology: optimizing transition and lung function in preterm infants.Pediatric research · 2025Article
- Respiratory Function in Ventilated Newborn Infants Nursed Prone and Supine.Pediatric pulmonology · 2025Observational
- Effect of high-frequency oscillatory ventilation with intermittent sigh breaths on carbon dioxide levels in neonates.Clinical and experimental pediatrics · 2025Article
- Central venous pressure dynamics in neonates with hypoxic-ischemic encephalopathy: insights into high mean airway pressure, PPHN, and ECMO management.Frontiers in pediatrics · 2025Article
- Association between fentanyl use and reduced risk of tension pneumothorax in extremely preterm infants born at 22-23 weeks' gestation: a retrospective case-control study.Frontiers in pediatrics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High-frequency ventilation (HFV) has been used as a respiratory support mode for neonates for over 30 years. HFV is characterized by delivering tidal volumes close to or less than the anatomical dead space. Both animal and clinical studies have shown that HFV can effectively restore lung function, and potentially limit ventilator-induced lung injury, which is considered an important risk factor for developing bronchopulmonary dysplasia (BPD). Knowledge of how HFV works, how it influences cardiorespiratory physiology, and how to apply it in daily clinical practice has proven to be essential for its optimal and safe use. We will present important aspects of gas exchange, lung-protective concepts, clinical use, and possible adverse effects of HFV. We also discuss the study results on the use of HFV in respiratory distress syndrome in preterm infants and respiratory failure in term neonates. IMPACT: Knowledge of how HFV works, how it influences cardiorespiratory physiology, and how to apply it in daily clinical practice has proven to be essential for its optimal and safe use. Therefore, we present important aspects of gas exchange, lung-protective concepts, clinical use, and possible adverse effects of HFV. The use of HFV in daily clinical practice in lung recruitment, determination of the optimal continuous distending pressure and frequency, and typical side effects of HFV are discussed. We also present study results on the use of HFV in respiratory distress syndrome in preterm infants and respiratory failure in term neonates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.