Evidence map›Paper›PMID 35136190›Full record

ArticleCommunications biology2022

In situ monitoring reveals cellular environmental instabilities in human pluripotent stem cell culture.

Shannon G Klein, Samhan M Alsolami, Silvia Arossa, Gerardo Ramos-Mandujano, Anieka J Parry, Alexandra Steckbauer, Carlos M Duarte, Mo Li

Abstract read
In one paragraph

Article in Communications biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  5. Nanobiodevices and quantum life science for future healthcare.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Review
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  15. Toward Best Practices for Controlling Mammalian Cell Culture Environments.Frontiers in cell and developmental biology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shannon G Klein *Red Sea Research Center (RSRC) and Computational Bioscience Research Center (CBRC), King Abdullah University of Science and Technology, Thuwal, 23955, Saudi Arabia.
Samhan M Alsolami *Biological and Environmental Science and Engineering Division (BESE), King Abdullah University of Science and Technology, Thuwal, 23955, Saudi Arabia.
Silvia ArossaRed Sea Research Center (RSRC) and Computational Bioscience Research Center (CBRC), King Abdullah University of Science and Technology, Thuwal, 23955, Saudi Arabia.
Gerardo Ramos-MandujanoBiological and Environmental Science and Engineering Division (BESE), King Abdullah University of Science and Technology, Thuwal, 23955, Saudi Arabia.
Anieka J ParryRed Sea Research Center (RSRC) and Computational Bioscience Research Center (CBRC), King Abdullah University of Science and Technology, Thuwal, 23955, Saudi Arabia.ORCID 0000-0002-4090-5782
Alexandra SteckbauerRed Sea Research Center (RSRC) and Computational Bioscience Research Center (CBRC), King Abdullah University of Science and Technology, Thuwal, 23955, Saudi Arabia.ORCID 0000-0002-8477-2256
Carlos M DuarteRed Sea Research Center (RSRC) and Computational Bioscience Research Center (CBRC), King Abdullah University of Science and Technology, Thuwal, 23955, Saudi Arabia. carlos.duarte@kaust.edu.sa.ORCID 0000-0002-1213-1361
Mo LiBiological and Environmental Science and Engineering Division (BESE), King Abdullah University of Science and Technology, Thuwal, 23955, Saudi Arabia. mo.li@kaust.edu.sa.ORCID 0000-0003-0827-8907

Funding

King Abdullah University of Science and Technology (KAUST) BAS/1/1080-01King Abdullah University of Science and Technology (KAUST) URF/1/3412-01-01
6 · The paper itself

Abstract

Mammalian cell cultures are a keystone resource in biomedical research, but the results of published experiments often suffer from reproducibility challenges. This has led to a focus on the influence of cell culture conditions on cellular responses and reproducibility of experimental findings. Here, we perform frequent in situ monitoring of dissolved O

Indexed as

Pluripotent Stem CellsAnimalsCell Culture TechniquesCell ProliferationCulture MediaHumansMammalsReproducibility of ResultsCulture Media

Identifiers

PMID35136190
PMCPMC8826360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.