Evidence map›Paper›PMID 35136157›Full record

ArticleScientific reports2022

Association between birth weight and neurodevelopmental disorders assessed using the Korean National Health Insurance Service claims data.

In Gyu Song, Han-Suk Kim, Yoon-Min Cho, You-Na Lim, Duk-Soo Moon, Seung Han Shin, Ee-Kyung Kim, Joonsik Park, Jeong Eun Shin, Jungho Han and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  10. Mechanisms of neurodevelopmental toxicity of topiramate.Critical reviews in toxicology · 2024
    Review
  11. Article
  12. Neurodevelopmental outcomes of preterm infants.Clinical and experimental pediatrics · 2023
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

In Gyu SongDepartment of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Han-Suk KimDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul National University College of Medicine, 101, Daehak-ro, Jungno-gu, Seoul, 03080, Republic of Korea. kimhans@snu.ac.kr.
Yoon-Min ChoHealth Insurance Research Institute, National Health Insurance Service, Wonju, South Korea.
You-Na LimGraduate School of Public Health, Seoul National University, Seoul, South Korea.
Duk-Soo MoonDepartment of Psychiatry, Jeju National University Hospital, Jeju, South Korea.
Seung Han ShinDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul National University College of Medicine, 101, Daehak-ro, Jungno-gu, Seoul, 03080, Republic of Korea.
Ee-Kyung KimDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul National University College of Medicine, 101, Daehak-ro, Jungno-gu, Seoul, 03080, Republic of Korea.
Joonsik ParkDepartment of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Jeong Eun ShinDepartment of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Jungho HanDepartment of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Ho Seon EunDepartment of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Yonsei University · KRSeoul National University Children's Hospital · KRJeju National University Hospital · KRKorea University Medical Center · KRNational Health Insurance Service · KRSeoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The risk of neurodevelopmental disorders in low birth weight (LBW) infants has gained recognition but remains debatable. We investigated the risk of attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) in school-aged children according to their birth weight. We conducted a retrospective cohort study using the Korean National Health Insurance claims data of 2,143,652 children who were born between 2008 and 2012. Gestational age of infants was not available; thus, outcomes were not adjusted with it. Not only infants with birth weights of < 1.5 kg, but also 2.0-2.4 kg and 1.5-1.9 kg were associated with having ADHD; odds ratio (OR), 1.41 (95% confidence interval [CI] 1.33-1.50), and 1.49 (95% CI 1.33-1.66), respectively. The OR in infants with birth weights of 2.0-2.4 kg and 1.5-1.9 kg was 1.91 (95% CI 1.79-2.05) and 3.25 (95% CI 2.95-3.59), respectively, indicating increased odds of having ASD. Subgroup analysis for children without perinatal diseases showed similar results. In this national cohort, infants with birth weights of < 2.5 kg were associated with ADHD and ASD, regardless of perinatal history. Children born with LBW need detailed clinical follow-up.

Indexed as

Attention Deficit Disorder with HyperactivityAutism Spectrum DisorderBirth WeightChildChild, PreschoolFemaleHumansMaleNational Health ProgramsNeurodevelopmental DisordersRepublic of KoreaRetrospective StudiesRiskRisk Factors

Identifiers

PMID35136157
PMCPMC8827104
OpenAlexW4210894964

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.