Evidence map›Paper›PMID 35135973›Full record

ArticleTransplantation2022

The Combined Roles of Race/Ethnicity and Substance Use in Predicting Likelihood of Kidney Transplantation.

Richelle N DeBlasio, Larissa Myaskovsky, Andrea F DiMartini, Emilee Croswell, Donna M Posluszny, Chethan Puttarajappa, Galen E Switzer, Ron Shapiro, Annette J DeVito Dabbs, Amit D Tevar and 2 more

Open access · greenAbstract read
In one paragraph

Article in Transplantation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Recentering Accountability for Disparities in Kidney Transplant Access.Journal of the American Society of Nephrology : JASN · 2024
    Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Richelle N DeBlasioDepartment of Psychiatry, University of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, PA.
Larissa MyaskovskyDepartment of Internal Medicine, Center for Healthcare Equity in Kidney Disease, University of New Mexico School of Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM.
Andrea F DiMartiniDepartment of Psychiatry, University of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, PA.
Emilee CroswellDepartment of Psychiatry, University of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, PA.
Donna M PoslusznyDepartment of Medicine, University of Pittsburgh, Pittsburgh, PA.
Chethan PuttarajappaDepartment of Medicine, University of Pittsburgh, Pittsburgh, PA.
Galen E SwitzerDepartment of Psychiatry, University of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, PA.
Ron ShapiroMount Sinai Recanati/Miller Transplantation Institute, Icahn School of Medicine, New York, NY.
Annette J DeVito DabbsAcute and Tertiary Care, School of Nursing, University of Pittsburgh, Pittsburgh, PA.
Amit D TevarDepartment of Surgery and Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA.
Sundaram HariharanDepartment of Medicine, University of Pittsburgh, Pittsburgh, PA.
Mary Amanda DewDepartment of Psychiatry, University of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, PA.
University of Pittsburgh · USUPMC Hillman Cancer Center · USVA Pittsburgh Healthcare System · US

Funding

Promoting diversity in research careers in diabetes, digestive and kidney diseasesR25DK078381 · NIDDK · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI MATTERS, GAIL L., REEVES, WILLIAM BRIAN · 2007 to 2024
$4.6M
Understanding Race and Culture in Living Donor Kidney TransplantationR01DK081325 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MYASKOVSKY, LARISSA · 2009 to 2013
$1.4M
NIDDK NIH HHS R01 DK081325NIDDK NIH HHS R25 DK078381
6 · The paper itself

Abstract

backgroundRacial/ethnic minorities face known disparities in likelihood of kidney transplantation. These disparities may be exacerbated when coupled with ongoing substance use, a factor also reducing likelihood of transplantation. We examined whether race/ethnicity in combination with ongoing substance use predicted incidence of transplantation.

methodsPatients were enrolled between March 2010 and October 2012 at the time of transplant evaluation. Substance use data were retrieved from transplant evaluations. Following descriptive analyses, the primary multivariable analyses evaluated whether, relative to the referent group (White patients with no substance use), racial/ethnic minority patients using any substances at the time of evaluation were less likely to receive transplants by the end of study follow-up (August 2020).

resultsAmong 1152 patients, 69% were non-Hispanic White, 23% non-Hispanic Black, and 8% Other racial/ethnic minorities. White, Black, and Other patients differed in percentages of current tobacco smoking (15%, 26%, and 18%, respectively; P = 0.002) and illicit substance use (3%, 8%, and 9%; P < 0.001) but not heavy alcohol consumption (2%, 4%, and 1%; P = 0.346). Black and Other minority patients using substances were each less likely to receive transplants than the referent group (hazard ratios ≤0.45, P ≤ 0.021). Neither White patients using substances nor racial/ethnic minority nonusers differed from the referent group in transplant rates. Additional analyses indicated that these effects reflected differences in waitlisting rates; once waitlisted, study groups did not differ in transplant rates.

conclusionsThe combination of minority race/ethnicity and substance use may lead to unique disparities in likelihood of transplantation. To facilitate equity, strategies should be considered to remove any barriers to referral for and receipt of substance use care in racial/ethnic minorities.

Indexed as

Kidney TransplantationSubstance-Related DisordersEthnic and Racial MinoritiesEthnicityHealthcare DisparitiesHumansMinority GroupsUnited States

Identifiers

PMID35135973
PMCPMC9169160
OpenAlexW4210853523

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.