Evidence map›Paper›PMID 35135916›Full record

ArticleInternal medicine (Tokyo, Japan)2022

Erdheim-Chester Disease Involving the Central Nervous System with Latent Toxoplasmosis.

Tomoya Wadayama, Mikito Shimizu, Ikko Kimura, Kousuke Baba, Goichi Beck, Seiichi Nagano, Ryo Morita, Hidenori Nakagawa, Michinori Shirano, Tetsushi Goto and 4 more

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Tomoya WadayamaDepartment of Neurology, Osaka University Graduate School of Medicine, Japan.
Mikito ShimizuDepartment of Neurology, Osaka University Graduate School of Medicine, Japan.
Ikko KimuraGraduate School of Frontier Biosciences, Osaka University, Japan.
Kousuke BabaDepartment of Neurology, Osaka University Graduate School of Medicine, Japan.
Goichi BeckDepartment of Neurology, Osaka University Graduate School of Medicine, Japan.
Seiichi NaganoDepartment of Neurology, Osaka University Graduate School of Medicine, Japan.
Ryo MoritaDepartment of Infectious Diseases, Osaka City General Hospital, Japan.
Hidenori NakagawaDepartment of Infectious Diseases, Osaka City General Hospital, Japan.
Michinori ShiranoDepartment of Infectious Diseases, Osaka City General Hospital, Japan.
Tetsushi GotoDepartment of Infectious Diseases, Osaka City General Hospital, Japan.
Kazumi NoroseDepartment of Infection and Host Defense, Graduate School of Medicine, Chiba University, Japan.
Kenji HikosakaDepartment of Infection and Host Defense, Graduate School of Medicine, Chiba University, Japan.
Shigeo MurayamaDepartment of Neurology, Osaka University Graduate School of Medicine, Japan.
Hideki MochizukiDepartment of Neurology, Osaka University Graduate School of Medicine, Japan.
Osaka University · JPOsaka City General Hospital · JPChiba University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Erdheim-Chester disease (ECD) is a rare, non-Langerhans cell histiocytosis characterized by the infiltration of foamy histiocytes into multiple organs. We herein report a case of ECD with central nervous system (CNS) involvement in a 63-year-old man who also presented a positive result for Toxoplasma gondii nested polymerase chain reaction testing of cerebrospinal fluid. Since anti-Toxoplasma treatment proved completely ineffective, we presumed latent infection of the CNS with T. gondii. This case suggests the difficulty of distinguishing ECD with CNS involvement from toxoplasmic encephalitis and the possibility of a relationship between the pathogeneses of ECD and infection with T. gondii.

Indexed as

Erdheim-Chester DiseaseHistiocytosis, Non-Langerhans-CellToxoplasmosisCentral Nervous SystemHumansMaleMiddle AgedErdheim-Chester diseasehistiocytosisneuro-oncologyToxoplasma nested polymerase chain reactiontoxoplasmosis

Identifiers

PMID35135916
PMCPMC9492489
OpenAlexW4210929406

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.