ArticleProceedings of the National Academy of Sciences of the United States of America2022
Functional network topography of the medial entorhinal cortex.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Impaired spatial coding and neuronal hyperactivity in the medial entorhinal cortex of aged APP knock-in mice.Cell reports · 2026Article
- Coordinating Cognition: The Entorhinal Cortex in Mnemonic, Temporal and Spatial Representation.Cells · 2026Review
- Diverse Neuronal Activity in Barrel Cortex During Self-Grooming and Whisking in Mice.Neuroscience bulletin · 2026Article
- Local lateral connectivity is sufficient for replicating cortex-like topographical organization in deep neural networks.Nature communications · 2026Article
- High-throughput two-photon volumetric brain imaging in freely moving mice.Nature communications · 2025Article
- A versatile miniature two-photon microscope enabling multicolor deep-brain imaging.Nature methods · 2025Article
- The medial entorhinal cortex encodes multisensory spatial information.Cell reports · 2024Article
- Article
- A unifying framework for functional organization in early and higher ventral visual cortex.Neuron · 2024Article
- Uncovering 2-D toroidal representations in grid cell ensemble activity during 1-D behavior.Nature communications · 2024Article
- A consistent map in the medial entorhinal cortex supports spatial memory.Nature communications · 2024Article
- Tests for learning and memory in rodent regulatory studies.Current research in toxicology · 2024Article
- Article
- Article
- Grid cells in rats deprived of geometric experience during development.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- A consistent map in the medial entorhinal cortex supports spatial memory.bioRxiv : the preprint server for biology · 2023Article
- A Unifying Principle for the Functional Organization of Visual Cortex.bioRxiv : the preprint server for biology · 2023Article
- Miniature three-photon microscopy maximized for scattered fluorescence collection.Nature methods · 2023Article
- Excitatory-inhibitory recurrent dynamics produce robust visual grids and stable attractors.Cell reports · 2022Article
- Profile of May-Britt and Edvard Moser.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The medial entorhinal cortex (MEC) creates a map of local space, based on the firing patterns of grid, head-direction (HD), border, and object-vector (OV) cells. How these cell types are organized anatomically is debated. In-depth analysis of this question requires collection of precise anatomical and activity data across large populations of neurons during unrestrained behavior, which neither electrophysiological nor previous imaging methods fully afford. Here, we examined the topographic arrangement of spatially modulated neurons in the superficial layers of MEC and adjacent parasubiculum using miniaturized, portable two-photon microscopes, which allow mice to roam freely in open fields. Grid cells exhibited low levels of co-occurrence with OV cells and clustered anatomically, while border, HD, and OV cells tended to intermingle. These data suggest that grid cell networks might be largely distinct from those of border, HD, and OV cells and that grid cells exhibit strong coupling among themselves but weaker links to other cell types.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.