Evidence map›Paper›PMID 35135881›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Stochastic microbiome assembly depends on context.

Eric W Jones, Jean M Carlson, David A Sivak, William B Ludington

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 92 citations in OpenAlex.

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  12. Human microbiome acquisition and transmission.Nature reviews. Microbiology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Eric W JonesDepartment of Physics, Simon Fraser University, Burnaby, BC V5A 1S6, Canada; eric_jones_2@sfu.ca.ORCID 0000-0001-8494-7899
Jean M CarlsonComplex Systems Group, Department of Physics, University of California, Santa Barbara, CA 93106.
David A SivakDepartment of Physics, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.ORCID 0000-0003-4815-4722
William B LudingtonDepartment of Embrylogy, Carnegie Institution for Science, Baltimore, MD 21218.ORCID 0000-0001-9637-4493
Simon Fraser University · CAJohns Hopkins University · USUniversity of California, Santa Barbara · US

Funding

Developing a reduced complexity model gut microbiome in the behavior model, Drosophila melanogasterDP5OD017851 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI LUDINGTON, WILLIAM BASIL · 2013 to 2017
$2.0M
NIH HHS DP5 OD017851
6 · The paper itself

Abstract

Observational studies reveal substantial variability in microbiome composition across individuals. Targeted studies in gnotobiotic animals underscore this variability by showing that some bacterial strains colonize deterministically, while others colonize stochastically. While some of this variability can be explained by external factors like environmental, dietary, and genetic differences between individuals, in this paper we show that for the model organism

Indexed as

MicrobiotaAnimalsBacteriaBacterial Physiological PhenomenaDrosophila melanogasterModels, BiologicalSpecies SpecificityStochastic Processescommunity assemblyDrosophilaecological interactionsmicrobiome

Identifiers

PMID35135881
PMCPMC8851475
OpenAlexW4210864836

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.