Evidence map›Paper›PMID 35135691›Full record

ArticleMayo Clinic proceedings2022

Risk of an Opioid-Related Emergency Department Visit or Hospitalization Among Older Breast, Colorectal, Lung, and Prostate Cancer Survivors.

Derrick C Gibson, Mukaila A Raji, Holly M Holmes, Jacques G Baillargeon, Yong-Fang Kuo

Abstract read
In one paragraph

Article in Mayo Clinic proceedings, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Derrick C GibsonDepartment of Preventive Medicine and Population Health, University of Texas Medical Branch, Galveston. Electronic address: degibson@utmb.edu.
Mukaila A RajiDivision of Geriatrics and Palliative Medicine, Department of Internal Medicine, University of Texas Medical Branch, Galveston.
Holly M HolmesDivision of Geriatrics and Palliative Medicine, Department of Internal Medicine, University of Texas Health Science Center, Houston.
Jacques G BaillargeonDepartment of Preventive Medicine and Population Health, Office of Biostatistics, University of Texas Medical Branch, Galveston.
Yong-Fang KuoDepartment of Preventive Medicine and Population Health, Office of Biostatistics, University of Texas Medical Branch, Galveston.

Funding

Pattern, Variation and Outcomes of Opioid Prescription in Older AdultsR01DA039192 · NIDA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI KUO, YONG-FANG, RAJI, MUKAILA A · 2016 to 2023
$3.1M
Opioid Prescribing and Health outcomes among Cancer SurvivorsF30CA254479 · NCI · UNIVERSITY OF TEXAS MED BR GALVESTON · PI GIBSON, DERRICK CHRISTIAN · 2020 to 2022
$106k
NCI NIH HHS F30 CA254479NIDA NIH HHS R01 DA039192
6 · The paper itself

Abstract

objectiveTo assess whether long-term cancer survivors (≥5 years after diagnosis) are at an increased risk of experiencing an opioid-related emergency department (ED) visit or hospitalization compared with persons without cancer.

methodsA 1:1 matched retrospective cohort study was performed using the Surveillance, Epidemiology, and End Results-Medicare linked data sets. The analysis was conducted from October 2020 to December 2020 in persons who lived 5 years or more after a breast, colorectal, lung, or prostate cancer diagnosis matched to noncancer controls on the basis of age, sex, race, pain conditions, and previous opioid use. Fine-Gray regression models were used to assess the relationship between cancer survivorship status and opioid-related ED visit or hospitalization.

resultsThe incidence of opioid-related ED visits and hospitalizations was 51.2 (95% CI, 43.5 to 59.8) and 62.2 (95% CI, 53.4 to 72.1) per 100,000 person-years among cancer survivors and matched noncancer controls, respectively. No significant association was observed between survivorship and opioid-related adverse event among opioid naive (hazard ratio, 0.79; 95% CI, 0.61 to 1.02) and non-naive (hazard ratio, 1.26; 95% CI, 0.84 to 1.89) cohorts.

conclusionCancer survivors and noncancer controls had a similar risk of an ED visit or inpatient admission. Guidelines and policies should promote nonopioid pain management approaches especially to opioid non-naive older adults, a population at high risk for an opioid-related ED visit or hospitalization.

Indexed as

Cancer SurvivorsColorectal NeoplasmsProstatic NeoplasmsAgedAnalgesics, OpioidEmergency Service, HospitalHospitalizationHumansLungMaleMedicareProstateRetrospective StudiesUnited StatesAnalgesics, Opioid

Identifiers

PMID35135691
PMCPMC8898260

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.