Evidence map›Paper›PMID 35135593›Full record

ArticleBMC research notes2022

The effect of estrogen on brown adipose tissue activity in male rats.

W Sievers, C Kettle, R A Green, L Van Schaik, M W Hale, H R Irving, D R Whelan, J A Rathner

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC research notes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

W SieversDepartment of Pharmacy and Biomedical Sciences, La Trobe University, Bendigo, VIC, Australia. w.sievers@latrobe.edu.au.ORCID http://orcid.org/0000-0001-6452-6325
C KettleDepartment of Pharmacy and Biomedical Sciences, La Trobe University, Bendigo, VIC, Australia.
R A GreenDepartment of Pharmacy and Biomedical Sciences, La Trobe University, Bendigo, VIC, Australia.
L Van SchaikDepartment of Pharmacy and Biomedical Sciences, La Trobe University, Bendigo, VIC, Australia.
M W HaleDepartment of Psychology and Counselling, La Trobe University, Bundoora, VIC, Australia.
H R IrvingDepartment of Pharmacy and Biomedical Sciences, La Trobe University, Bendigo, VIC, Australia.
D R WhelanDepartment of Pharmacy and Biomedical Sciences, La Trobe University, Bendigo, VIC, Australia.
J A RathnerDepartment of Pharmacy and Biomedical Sciences, La Trobe University, Bendigo, VIC, Australia.
La Trobe University · AUThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCentrally administered estrogen can increase sympathetic nerve activity to brown adipose tissue, resulting in thermogenesis. The central thermogenic effects of estrogen have not been investigated in males. Therefore, this study sought to investigate the effects of peripherally and centrally administered estrogen on thermogenesis, heart rate and mean arterial pressure in male rats. Thermogenesis was assessed by monitoring brown adipose tissue temperature.

resultsPeripherally administered estrogen elicited no significant effect on brown adipose tissue temperature, heart rate or mean arterial pressure. Centrally administered estrogen elicited a coincident increase in both brown adipose tissue and core temperature. Centrally administered estrogen also resulted in a decrease in mean arterial pressure but had no effect on heart rate. With the present data it is not possible to elucidate whether changes in temperature were the result of thermogenic or thermoregulatory mechanisms.

Indexed as

Adipose Tissue, BrownThermogenesisAnimalsEstrogensHeart RateMaleRatsSympathetic Nervous SystemEstrogensRodentsThermogenesisThermoregulationTranswomen

Identifiers

PMID35135593
PMCPMC8822813
OpenAlexW4210894787

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.