ArticleCirculation. Heart failure2022
Association of Pulmonary Artery Pulsatility Index With Adverse Cardiovascular Events Across a Hospital-Based Sample.
Article in Circulation. Heart failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 42 citations in OpenAlex.
- Integrated Hemodynamic Measures of Cardiac Function and Association With Clinical Outcomes.JACC. Advances · 2026Article
- Predictive Value of the Pulmonary Artery Pulsatility Index in Pulmonary Arterial Hypertension: REVEAL Analysis.Cardiology research · 2026Article
- Sex Differences in Pulmonary Hypertension and Associated Right Ventricular Dysfunction.The American journal of cardiology · 2026Article
- Pulmonary artery compliance in aortic stenosis: protective or maladaptive? Rethinking the conclusions on PAPi prognostic value.ESC heart failure · 2025Article
- Reply to letter to the editor.ESC heart failure · 2025Article
- Impact of the New Definition on the Prognosis of Patients With Pulmonary Hypertension Compared to the Classic Definition.Korean circulation journal · 2025Article
- Article
- The pulmonary artery pulsatility index in patients with severe aortic stenosis undergoing valve replacement.ESC heart failure · 2025Article
- The Right Approach: Power of Biomarkers in the Assessment and Management of Right Ventricular Dysfunction.International journal of molecular sciences · 2025Review
- The VTI-VeXUS Index in Septic Shock: An Exploratory Proof-of-Concept Observational Study of a Novel Hemodynamic Parameter.Journal of clinical medicine · 2025Article
- Advanced Markers for Hemodynamic Monitoring in Cardiogenic Shock and End-Stage Heart Failure: A Mini Review.Heart failure reviews · 2025Review
- Novel Hemodynamic Markers and Kidney Function in Patients with Acute Decompensated Heart Failure.Kidney360 · 2025Article
- Echocardiography-Based Pulmonary Artery Pulsatility Index Correlates with Outcomes in Patients with Acute Pulmonary Embolism.Journal of clinical medicine · 2025Article
- Pulmonary Artery Pulsatility Index in Acute and Chronic Pulmonary Embolism.Medicina (Kaunas, Lithuania) · 2025Article
- Low Aortic Pulsatility Index and Pulmonary Artery Pulsatility Index Are Associated With Increased Mortality in Patients With Dilated Cardiomyopathy Awaiting Heart Transplantation.Korean circulation journal · 2025Article
- Dynamic assessment of left ventricular coupling and myocardial reserve in patients with cardiogenic shock.European heart journal open · 2024Article
- Pulmonary Artery Pressures and Mortality During Venoarterial ECMO: An ELSO Registry Analysis.Circulation. Heart failure · 2024Article
- Management of cardiogenic shock: a narrative review.Annals of intensive care · 2024Review
- Monitoring a Mystery: The Unknown Right Ventricle during Left Ventricular Unloading with Impella in Patients with Cardiogenic Shock.Journal of clinical medicine · 2024Article
- The Association of the Pulmonary Artery Pulsatility Index and Right Ventricular Function after Cardiac Surgery.Critical care research and practice · 2024Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundThe pulmonary artery pulsatility index (PAPi), calculated from the ratio of the pulmonary artery pulse pressure to right atrial pressure, is a predictor of right ventricular failure after inferior myocardial infarction and left ventricular assist device implantation. Whether PAPi is associated with adverse outcomes across a heterogeneous population is unknown.
methodsWe examined consecutive patients undergoing right heart catheterization between 2005 and 2016 in a hospital-based cohort. Multivariable Cox models were utilized to examine the association between PAPi and all-cause mortality, major adverse cardiac events, and heart failure hospitalizations.
resultsWe studied 8285 individuals (mean age 63 years, 39% women) with median PAPi across quartiles 1.7, 2.8, 4.2, and 8.7, who were followed over a mean follow-up of 6.7±3.3 years. Patients in the lowest PAPi quartile had a 60% greater risk of death compared with the highest quartile (multivariable-adjusted hazard ratio, 1.60 [95% CI, 1.36-1.88],
conclusionsCompared with the highest PAPi quartile, patients in PAPi quartiles 1 to 3 had a greater risk of all-cause mortality, major adverse cardiac events, and heart failure hospitalizations, with greatest risk observed in the lowest quartile. A low PAPi, even at values higher than previously reported, may serve an important role in identifying high-risk individuals across a broad spectrum of cardiovascular disease.
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