Evidence map›Paper›PMID 35135166›Full record

ArticleJCO precision oncology2018

Circulating

Priyanka C Iyer, Gilbert J Cote, Tao Hai, Maria Gule-Monroe, Jacquelin Bui-Griffith, Michelle D Williams, Kenneth Hess, Marie-Claude Hofmann, Ramona Dadu, Mark Zafereo and 8 more

Open access · bronzeAbstract read
In one paragraph

Article in JCO precision oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Detection of theJournal of clinical medicine · 2024
    Review
  12. Review
  13. Review
  14. Review
  15. Clinical Utility of Circulating Cell-Free DNA Mutations in Anaplastic Thyroid Carcinoma.Thyroid : official journal of the American Thyroid Association · 2021
    Article
  16. Opportunities and Challenges of Liquid Biopsy in Thyroid Cancer.International journal of molecular sciences · 2021
    Review
  17. Molecular-Driven Therapy in Advanced Thyroid Cancer.Current treatment options in oncology · 2021
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 4 countries.

Priyanka C IyerThe University of Texas MD Anderson Cancer Center, Houston, TX.
Gilbert J CoteThe University of Texas MD Anderson Cancer Center, Houston, TX.
Tao HaiThe University of Texas MD Anderson Cancer Center, Houston, TX.
Maria Gule-MonroeThe University of Texas MD Anderson Cancer Center, Houston, TX.
Jacquelin Bui-GriffithThe University of Texas MD Anderson Cancer Center, Houston, TX.
Michelle D WilliamsThe University of Texas MD Anderson Cancer Center, Houston, TX.
Kenneth HessThe University of Texas MD Anderson Cancer Center, Houston, TX.
Marie-Claude HofmannThe University of Texas MD Anderson Cancer Center, Houston, TX.
Ramona DaduThe University of Texas MD Anderson Cancer Center, Houston, TX.
Mark ZafereoThe University of Texas MD Anderson Cancer Center, Houston, TX.
Naifa L BusaidyThe University of Texas MD Anderson Cancer Center, Houston, TX.
Renata FerrarottoThe University of Texas MD Anderson Cancer Center, Houston, TX.
Vivek SubbiahThe University of Texas MD Anderson Cancer Center, Houston, TX.
Neil GrossThe University of Texas MD Anderson Cancer Center, Houston, TX.
Brandon G GunnThe University of Texas MD Anderson Cancer Center, Houston, TX.
Heath D SkinnerThe University of Texas MD Anderson Cancer Center, Houston, TX.
Adam S GardenThe University of Texas MD Anderson Cancer Center, Houston, TX.
Maria E CabanillasThe University of Texas MD Anderson Cancer Center, Houston, TX.
OncoMed (United States) · USAstraZeneca (Brazil) · BRMerck Serono (Italy) · ITMerck (Germany) · DEThe University of Texas MD Anderson Cancer Center · USBristol-Myers Squibb (Germany) · DE

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
The Ohio State University and MD Anderson Cancer Center Thyroid Cancer SPOREP50CA168505 · NCI · OHIO STATE UNIVERSITY · PI DE LA CHAPELLE, ALBERT · 2013 to 2017
$10.9M
NCI NIH HHS P30 CA016672NCI NIH HHS P50 CA168505
6 · The paper itself

Abstract

Purpose: Anaplastic thyroid cancer (ATC) is a deadly form of thyroid cancer. Materials and Methods: The ddPCR assay was evaluated for its sensitivity, specificity for detection of Results: Forty-four patients with ATC who were tested for the Conclusion: cfDNA detection by ddPCR is highly sensitive, specific, and concordant with mutation status on ATC tumors. ddPCR also can be used for monitoring cfDNA levels in conjunction with imaging scans in patients with ATC.

Identifiers

PMID35135166
PMCPMC9797231
OpenAlexW2904321558

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.